Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MLNR | O43193 | 1/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8649503 | 0.87 | FDPS (0.48) | FDPSMEN1KMT2ALMNATP53 | |
| SCHEMBL8843664 | 0.85 | FDPS (0.47) | FDPSMEN1KMT2ALMNATP53 | |
| SCHEMBL8646454 | 0.83 | FDPS (0.44) | FDPSMEN1KMT2ALMNATP53 | |
| SCHEMBL8843563 | 0.80 | FDPS (0.42) | FDPSMEN1KMT2ALMNATP53 | |
| SCHEMBL8842640 | 0.76 | METAP1 (0.41) | FDPSGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL8842783 | 0.74 | METAP1 (0.40) | FDPSGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL8646908 | 0.74 | SLC6A1 (0.45) | FDPSMEN1KMT2AALOX15ALDH1A1 | |
| SCHEMBL8701346 | 0.71 | FDPS (1.00) | FDPSMEN1KMT2ALMNATP53 | |
| SCHEMBL8645684 | 0.71 | FDPS (0.39) | FDPSMEN1KMT2AALOX15ALDH1A1 | |
| SCHEMBL8842578 | 0.71 | GRIN2D (0.33) | FDPSGRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0703919-B1 | PHOSPHOSUCCINIC ACID DERIVATIVES AND THEIR USE AS MEDICAMENTS | BOEHRINGER MANNHEIM GMBH (DE) | 1998-09-02 | — | — | EP | claimed |
| US-5627170-A | Phosphonic acid compound containing heterocyclic substituents, pharmaceutical composition contains same and a method of treating calcium metabolism disturbance | BOEHRINGER MANNHEIM GMBH (DE) | 1997-05-06 | — | — | US | disclosed |
| US-5538957-A | OSTEOPOROSIS | BOEHRINGER MANNHEIM GMBH (DE) | 1996-07-23 | — | — | US | disclosed |