Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 8/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | RARA | P10276 | 2/20 | 0.32 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | IKBKB | O14920 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8380382 | 0.87 | RARG (0.36) | RARGKIF11RARARARBIKBKB | |
| SCHEMBL9065459 | 0.87 | KIF11 (0.33) | RARGKIF11RARARARBMAPK1 | |
| SCHEMBL9361830 | 0.85 | RARG (0.36) | RARGKIF11RARARARBF2 | |
| SCHEMBL9252923 | 0.79 | RARG (0.32) | RARGMAPK1NPC1RAB9A | |
| SCHEMBL8550659 | 0.78 | RARG (0.33) | RARGKIF11MAPK1FFAR4NPC1 | |
| SCHEMBL8550666 | 0.77 | HTT (0.34) | RARGRARARARBIKBKBF2 | |
| SCHEMBL7962141 | 0.75 | BLM (0.37) | RARGRARARARBIKBKBF2 | |
| SCHEMBL8133892 | 0.75 | RAB9A (0.33) | RARGMAPK1NPC1RAB9A | |
| SCHEMBL8377229 | 0.75 | KIF11 (0.32) | KIF11 | |
| SCHEMBL7965969 | 0.75 | LMNA (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313305-B1 | ANTIBIOTICS, BACTERICIDES | HOECHST MARION ROUSSEL (FR) | 2001-11-06 | — | — | US | disclosed |
| US-5587372-A | BACERICIDES | ROUSSEL UCLAF (FR) | 1996-12-24 | — | — | US | disclosed |
| US-5455238-A | Bactericides | ROUSSEL UCLAF (FR) | 1995-10-03 | — | — | US | disclosed |