Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 13/20 | 0.48 |
| ▸ | NR3C1 | P04150 | 12/20 | 0.48 |
| ▸ | AR | P10275 | 10/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8652950 | 0.91 | PGR (0.48) | PGRNR3C1ARCYP3A4ABCB11 | |
| SCHEMBL8652174 | 0.88 | PGR (0.49) | PGRNR3C1ARCYP3A4ABCB11 | |
| SCHEMBL8650867 | 0.84 | PGR (0.49) | PGRNR3C1ARCYP3A4ABCB11 | |
| SCHEMBL8652053 | 0.83 | PGR (0.45) | PGRNR3C1ARCYP3A4ABCB11 | |
| SCHEMBL9019810 | 0.83 | PGR (0.65) | PGRNR3C1ARCYP3A4ABCB11 | |
| SCHEMBL8651931 | 0.81 | NR3C1 (0.49) | PGRNR3C1ARCYP3A4ABCB11 | |
| SCHEMBL8767965 | 0.79 | NR3C1 (0.46) | PGRNR3C1ARCYP3A4ABCB11 | |
| SCHEMBL8653263 | 0.78 | PGR (0.45) | PGRNR3C1ARCYP3A4MAPT | |
| SCHEMBL8664838 | 0.76 | PGR (0.45) | PGRNR3C1ARCYP3A4ABCB11 | |
| SCHEMBL8652943 | 0.76 | PGR (0.44) | PGRNR3C1ARCYP3A4ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567472-B1 | D-HOMO-(16-EN)-11 BETA-ARYL-4-ESTRENES, PROCESS FOR PRODUCING THEM AND THEIR USE AS MEDICAMENTS | SCHERING AG (DE) | 1998-10-07 | — | — | EP | claimed |