Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 3/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3006584 | 0.73 | KMT2A (0.59) | TRPA1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL7749485 | 0.70 | — | — | |
| SCHEMBL3800079 | 0.69 | TRPA1 (0.46) | TRPA1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL3801225 | 0.69 | TRPA1 (0.46) | TRPA1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL29109510 | 0.69 | — | — | |
| SCHEMBL10144182 | 0.68 | HPGD (0.45) | TRPA1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL5805024 | 0.68 | KMT2A (0.53) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL5805026 | 0.68 | KMT2A (0.53) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL8458208 | 0.67 | TRPA1 (0.62) | TRPA1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL29404696 | 0.66 | TRPA1 (1.00) | TRPA1MAPTKMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5688906-A | Highly efficient nonlinear optical polyimides | ENICHEM S.P.A. (IT) | 1997-11-18 | — | — | US | claimed |
| US-5679763-A | Polyquinoline-based nonlinear optical materials | ENICHEM S.P.A. (IT) | 1997-10-21 | — | — | US | claimed |
| EP-0729056-A1 | Polyquinoline-based nonlinear optical materials | ENICHEM S.p.A. (IT) | 1996-08-28 | — | — | EP | claimed |
| EP-0647874-A1 | Highly efficient nonlinear optical polyimides | ENICHEM S.p.A. (IT) | 1995-04-12 | — | — | EP | claimed |
| US-5736592-A | Process for intramolecularly condensing a non-linear optical polyamic acid composition | ENICHEM S.P.A. (IT) | 1998-04-07 | — | — | US | disclosed |
| US-5688906-A | Highly efficient nonlinear optical polyimides | ENICHEM S.P.A. (IT) | 1997-11-18 | — | — | US | disclosed |
| US-5679763-A | Polyquinoline-based nonlinear optical materials | ENICHEM S.P.A. (IT) | 1997-10-21 | — | — | US | disclosed |
| EP-0729056-A1 | Polyquinoline-based nonlinear optical materials | ENICHEM S.p.A. (IT) | 1996-08-28 | — | — | EP | disclosed |
| EP-0727692-A2 | Process for intramolecularly condensing a non-linear optical polyamic acid composition | ENICHEM S.p.A. (IT) | 1996-08-21 | — | — | EP | disclosed |
| EP-0647874-A1 | Highly efficient nonlinear optical polyimides | ENICHEM S.p.A. (IT) | 1995-04-12 | — | — | EP | disclosed |