Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GLS | O94925 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7551652 | 0.88 | PDGFRB (0.46) | L3MBTL1PTPN1NAMPTNPC1RAB9A | |
| SCHEMBL8651290 | 0.86 | PTPN1 (0.41) | L3MBTL1PTPN1NAMPTNPC1RAB9A | |
| SCHEMBL8650989 | 0.84 | PTPN1 (0.40) | L3MBTL1PTPN1NAMPTNPC1RAB9A | |
| SCHEMBL30290947 | 0.84 | DTYMK (0.44) | L3MBTL1GRM2NAMPTCA1CA2 | |
| SCHEMBL474165 | 0.84 | DTYMK (0.44) | L3MBTL1GRM2NAMPTCA1CA2 | |
| SCHEMBL5718757 | 0.84 | ALDH1A1 (0.47) | MEN1KMT2AHPGD | |
| SCHEMBL135312 | 0.83 | KMT2A (0.47) | L3MBTL1NAMPTCA1CA2HDAC1 | |
| SCHEMBL31305194 | 0.83 | KMT2A (0.47) | L3MBTL1NAMPTCA1CA2HDAC1 | |
| SCHEMBL8652880 | 0.83 | ALDH1A1 (0.41) | L3MBTL1GRM2NAMPTNPC1RAB9A | |
| SCHEMBL27840007 | 0.83 | L3MBTL1 (0.48) | L3MBTL1GRM2NAMPTCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719152-A | Tricyclic quinoxalinedione derivatives | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 1998-02-17 | — | — | US | disclosed |
| EP-0627434-A1 | Tricyclic quinoxalinedione derivatives | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1994-12-07 | — | — | EP | disclosed |