Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | NAMPT | P43490 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GLS | O94925 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8651290 | 0.94 | PTPN1 (0.41) | PTPN1NAMPTCA1CA2LMNA | |
| SCHEMBL7551652 | 0.87 | PDGFRB (0.46) | PTPN1NAMPTCA1CA2LMNA | |
| SCHEMBL8650394 | 0.84 | L3MBTL1 (0.42) | PTPN1NAMPTCA1CA2LMNA | |
| SCHEMBL8652875 | 0.83 | CA1 (0.43) | NAMPTCA1CA2GLSSMN1; SMN2 | |
| SCHEMBL22526720 | 0.79 | NAMPT (0.49) | NAMPTCA1CA2ALDH1A1TDP1 | |
| SCHEMBL5718757 | 0.79 | ALDH1A1 (0.47) | ALDH1A1MAPTCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL8650237 | 0.79 | L3MBTL1 (0.40) | PTPN1NAMPTLMNATDP1MAPT | |
| SCHEMBL31305194 | 0.78 | KMT2A (0.47) | NAMPTCA1CA2ALDH1A1TDP1 | |
| SCHEMBL135312 | 0.78 | KMT2A (0.47) | NAMPTCA1CA2ALDH1A1TDP1 | |
| SCHEMBL474165 | 0.77 | DTYMK (0.44) | NAMPTCA1CA2CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719152-A | Tricyclic quinoxalinedione derivatives | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 1998-02-17 | — | — | US | disclosed |
| EP-0627434-A1 | Tricyclic quinoxalinedione derivatives | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1994-12-07 | — | — | EP | disclosed |