Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 7/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7816528 | 0.75 | MAPT (0.35) | TSHRKIF11ALDH1A1MAOB | |
| SCHEMBL7203963 | 0.75 | LMNA (0.40) | KIF11TDP1 | |
| SCHEMBL27880149 | 0.74 | ALDH1A1 (0.38) | TSHRCYP1A2ALDH1A1CYP2C19HIF1A | |
| SCHEMBL342226 | 0.74 | ALDH1A1 (0.38) | TSHRCYP1A2ALDH1A1CYP2C19HIF1A | |
| SCHEMBL1148767 | 0.74 | KCNN4 (0.40) | TSHRKIF11ALDH1A1CYP2C19HIF1A | |
| SCHEMBL6311548 | 0.74 | ALDH1A1 (0.38) | TSHRCYP1A2ALDH1A1CYP2C19HIF1A | |
| SCHEMBL24683681 | 0.73 | KCNN4 (0.41) | CYP1A2KIF11ALDH1A1KCNN4 | |
| SCHEMBL10379349 | 0.73 | TDP1 (0.41) | KIF11TDP1 | |
| SCHEMBL10440076 | 0.72 | BCL2 (0.53) | ALDH1A1 | |
| SCHEMBL28194983 | 0.71 | GAA (0.38) | TSHRCYP1A2ALDH1A1CYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0435714-B2 | Process for the preparation of chlorinated carboxylic acid chlorides | POUDRES & EXPLOSIFS STE NALE (FR) | 1998-07-08 | — | — | EP | disclosed |
| EP-0435714-A2 | Process for the preparation of clorinated carboxylic acid clorides | SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) | 1991-07-03 | — | — | EP | disclosed |