Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12871836 | 0.88 | HTR1E (0.49) | SLC6A3CYP3A4LMNACHRM2HTR1A | |
| SCHEMBL517226 | 0.88 | HTR1E (0.49) | SLC6A3CYP3A4LMNACHRM2HTR1A | |
| SCHEMBL11932082 | 0.87 | SLC6A3 (0.46) | SLC6A3CYP3A4LMNACHRM2HTR1A | |
| SCHEMBL12115724 | 0.85 | SLC6A3 (0.57) | SLC6A3CYP3A4LMNACHRM2HTR1A | |
| SCHEMBL11932080 | 0.84 | SLC6A3 (0.41) | SLC6A3CYP3A4LMNACHRM2HTR1A | |
| SCHEMBL1179036 | 0.83 | SLC6A3 (0.44) | SLC6A3CYP3A4LMNACHRM2HTR1A | |
| SCHEMBL12871837 | 0.83 | SLC6A3 (0.44) | SLC6A3CYP3A4LMNACHRM2HTR1A | |
| SCHEMBL4247382 | 0.83 | SLC6A3 (0.65) | SLC6A3SLC6A2 | |
| SCHEMBL16162890 | 0.77 | SLC6A3 (0.44) | SLC6A3CYP3A4LMNACHRM2HTR1A | |
| SCHEMBL4242909 | 0.76 | ALOX5 (0.49) | SLC6A3LMNAMAPTHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750783-A | TREATMENT OF ATHEROSCLEROSIS | BAYER AKTIENGESELLSCHAFT (DE) | 1998-05-12 | — | — | US | disclosed |