Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 14/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 12/20 | 0.47 |
| ▸ | AR | P10275 | 12/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.36 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8651021 | 0.89 | PGR (0.48) | PGRNR3C1ARCYP3A4NR3C2 | |
| SCHEMBL8769036 | 0.88 | NR3C1 (0.44) | PGRNR3C1ARCYP3A4CYP2C8 | |
| SCHEMBL8651981 | 0.87 | NR3C1 (0.50) | PGRNR3C1ARCYP3A4CYP2C8 | |
| SCHEMBL9019806 | 0.86 | NR3C1 (0.61) | PGRNR3C1ARCYP3A4CYP2C8 | |
| SCHEMBL8650867 | 0.86 | PGR (0.49) | PGRNR3C1ARCYP3A4NR3C2 | |
| SCHEMBL8664838 | 0.86 | PGR (0.45) | PGRNR3C1ARCYP3A4NR3C2 | |
| SCHEMBL8651052 | 0.82 | PGR (0.46) | PGRNR3C1ARCYP3A4NR3C2 | |
| SCHEMBL8768257 | 0.79 | PGR (0.46) | PGRNR3C1ARCYP3A4NR3C2 | |
| SCHEMBL9019858 | 0.78 | SERPINA6 (0.51) | PGRNR3C1ARCYP3A4NR3C2 | |
| SCHEMBL8767837 | 0.77 | PGR (0.50) | PGRNR3C1ARCYP3A4NR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567472-B1 | D-HOMO-(16-EN)-11 BETA-ARYL-4-ESTRENES, PROCESS FOR PRODUCING THEM AND THEIR USE AS MEDICAMENTS | SCHERING AG (DE) | 1998-10-07 | — | — | EP | claimed |