Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.45 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 5/20 | 0.42 |
| ▸ | PPARG | P37231 | 3/20 | 0.42 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL258619 | 0.88 | HSP90AA1 (0.57) | HSP90AA1SOS1TSHRHSD17B10CA1 | |
| SCHEMBL9445002 | 0.87 | HSP90AA1 (0.50) | HSP90AA1SOS1SCN9AHSD17B3HSD17B2 | |
| SCHEMBL9623378 | 0.84 | ESR1 (0.58) | HSP90AA1TSHRHSD17B10CA1CA2 | |
| SCHEMBL27540591 | 0.84 | CACNA1C (0.44) | HSP90AA1SOS1SCN9APPARAPPARG | |
| SCHEMBL9467645 | 0.84 | FFAR1 (0.45) | HSP90AA1SOS1SCN9ATSHRHSD17B10 | |
| SCHEMBL7083294 | 0.82 | LTA4H (0.54) | HSP90AA1TSHRHSD17B10CA1CA2 | |
| SCHEMBL9445013 | 0.82 | HSP90AA1 (0.68) | HSP90AA1TSHRHSD17B10CA1CA2 | |
| SCHEMBL27486568 | 0.82 | FFAR1 (0.48) | PPARAPPARD | |
| SCHEMBL10704059 | 0.81 | CA1 (0.61) | HSP90AA1SOS1TSHRHSD17B10CA1 | |
| SCHEMBL13048707 | 0.81 | HSP90AA1 (0.47) | HSP90AA1SOS1TSHRHSD17B10CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0584046-B1 | Carbamic acid amide derivatives and their use as pesticides | CIBA GEIGY AG (CH) | 1998-10-07 | — | — | EP | disclosed |
| US-5648494-A | INSECTICIDES OR PESTICIDES | CIBA-GEIGY CORPORATION (US) | 1997-07-15 | — | — | US | disclosed |
| US-5393885-A | Agrichemical active materials useful in pest control | CIBA-GEIGY CORPORATION (US) | 1995-02-28 | — | — | US | disclosed |
| EP-0584046-A1 | Carbamic acid amide derivatives and their use as pesticides | CIBA-GEIGY AG (CH) | 1994-02-23 | — | — | EP | disclosed |