Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7336636 | 1.00 | ATM (0.47) | ATMALDH1A1ALOX5LTA4HEPHX2 | |
| SCHEMBL7336632 | 1.00 | ATM (0.47) | ATMALDH1A1ALOX5LTA4HEPHX2 | |
| SCHEMBL7336194 | 0.83 | LTA4H (0.46) | LTA4HEPHX2BCHE | |
| Hydrochloric Acid SCHEMBL7364278 | 0.82 | LTA4H (0.45) | LTA4HEPHX2BCHE | |
| SCHEMBL7367128 | 0.82 | ATM (0.51) | ATMALDH1A1L3MBTL1LMNAADAM17 | |
| SCHEMBL8638808 | 0.82 | ATM (0.51) | ATMALDH1A1L3MBTL1LMNAADAM17 | |
| SCHEMBL7367127 | 0.82 | ATM (0.51) | ATMALDH1A1L3MBTL1LMNAADAM17 | |
| SCHEMBL8650717 | 0.77 | NPC1 (0.41) | ALOX5LTA4HEPHX2L3MBTL1MAPT | |
| SCHEMBL7337139 | 0.77 | NPC1 (0.41) | ALOX5LTA4HEPHX2L3MBTL1MAPT | |
| SCHEMBL7328301 | 0.77 | NPC1 (0.41) | ALOX5LTA4HEPHX2L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711271-B1 | AMINOINDANES AND RELATED COMPOUNDS USEFUL AS CALCIUM-CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1998-10-07 | — | — | EP | disclosed |