Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 5/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | FLT1 | P17948 | 1/20 | 0.34 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | AR | P10275 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9018731 | 0.91 | SLC9A1 (0.42) | SLC9A1KCNH2CYP3A4CYP1A2ADORA3 | |
| SCHEMBL24525434 | 0.89 | NOTUM (0.50) | NOTUMCFTRSOS1KCNH2SIRT6 | |
| SCHEMBL8610045 | 0.87 | SLC9A1 (0.48) | SLC9A1CFTRKCNH2SIRT6SMN1; SMN2 | |
| SCHEMBL8608691 | 0.85 | SLC9A1 (0.40) | SLC9A1SIRT6PDGFRBFGFR1PDGFRA | |
| SCHEMBL8613931 | 0.83 | NOTUM (0.47) | SLC9A1NOTUMCFTRSOS1KCNH2 | |
| SCHEMBL8610545 | 0.83 | NOTUM (0.47) | SLC9A1NOTUMCFTRSOS1KCNH2 | |
| SCHEMBL8611003 | 0.81 | NOTUM (0.48) | SLC9A1NOTUMCFTRSOS1KCNH2 | |
| SCHEMBL8612597 | 0.80 | CFTR (0.48) | SLC9A1CFTRSIRT6CYP3A4CYP1A2 | |
| SCHEMBL8612363 | 0.79 | NOTUM (0.43) | SLC9A1NOTUMCFTRSOS1KCNH2 | |
| SCHEMBL8609014 | 0.79 | NOTUM (0.43) | SLC9A1NOTUMCFTRSOS1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5747539-A | Fluorine-containing benzoylguanidines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-05-05 | — | — | US | disclosed |