Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 6/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9018726 | 0.91 | SLC9A1 (0.50) | SLC9A1TDP1F2PRSS1PRSS2 | |
| SCHEMBL27386925 | 0.89 | TDP1 (0.47) | TDP1MAPTCFTRMEN1KMT2A | |
| SCHEMBL8653264 | 0.87 | SLC9A1 (0.41) | SLC9A1MAPTCFTRMEN1KMT2A | |
| SCHEMBL8610762 | 0.85 | SLC9A1 (0.47) | SLC9A1TDP1MEN1KMT2AF2 | |
| SCHEMBL8613944 | 0.83 | MAPT (0.44) | SLC9A1MAPTCFTRKCNH2 | |
| SCHEMBL8611156 | 0.81 | SLC9A1 (0.47) | SLC9A1MAPTCFTRKCNH2 | |
| SCHEMBL8612597 | 0.80 | CFTR (0.48) | SLC9A1TDP1MAPTCFTRMEN1 | |
| SCHEMBL8611424 | 0.78 | SLC9A1 (0.39) | SLC9A1MAPTCFTRKCNH2KDM4E | |
| SCHEMBL8612355 | 0.77 | TDP1 (0.47) | SLC9A1TDP1MAPTMEN1KMT2A | |
| SCHEMBL8608691 | 0.77 | SLC9A1 (0.40) | SLC9A1TDP1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5747539-A | Fluorine-containing benzoylguanidines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-05-05 | — | — | US | disclosed |