Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 17/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8948757 | 0.89 | MAPT (0.34) | MAPTLMNAHSD17B1RECQLSMN1; SMN2 | |
| SCHEMBL8768970 | 0.85 | PGR (0.33) | CYP19A1NR3C1PGRAR | |
| SCHEMBL8410289 | 0.84 | PGR (0.32) | NR3C1PGRAR | |
| SCHEMBL8651638 | 0.83 | MAPT (0.39) | MAPTLMNAHSD17B1RECQLSMN1; SMN2 | |
| SCHEMBL9174063 | 0.83 | MAPT (0.39) | MAPTLMNAHSD17B1RECQLSMN1; SMN2 | |
| SCHEMBL8768139 | 0.83 | MAPT (0.39) | MAPTLMNAHSD17B1RECQLSMN1; SMN2 | |
| SCHEMBL8653835 | 0.76 | MAPT (0.46) | MAPTLMNAHSD17B1RECQLSMN1; SMN2 | |
| SCHEMBL8407083 | 0.73 | CYP19A1 (0.37) | MAPTLMNAHSD17B1RECQLSMN1; SMN2 | |
| SCHEMBL8655553 | 0.72 | MAPT (0.35) | MAPTLMNAHSD17B1RECQLSMN1; SMN2 | |
| SCHEMBL8654560 | 0.72 | STS (0.38) | MAPTLMNAHSD17B1RECQLSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567472-B1 | D-HOMO-(16-EN)-11 BETA-ARYL-4-ESTRENES, PROCESS FOR PRODUCING THEM AND THEIR USE AS MEDICAMENTS | SCHERING AG (DE) | 1998-10-07 | — | — | EP | disclosed |
| US-5519027-A | PROGESTERONE ANTAGONIST FOR OXYTOCICS OR PREVENTION OF TERMINATION OF PREGNANCY | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-05-21 | — | — | US | disclosed |