Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 2/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8653384 | 0.84 | MAPT (0.38) | PGRNR3C1AR | |
| SCHEMBL8407453 | 0.83 | PGR (0.34) | PGRNR3C1AR | |
| SCHEMBL8768970 | 0.81 | PGR (0.33) | PGRNR3C1AR | |
| SCHEMBL8407252 | 0.75 | PGR (0.37) | PGRNR3C1AR | |
| SCHEMBL8410183 | 0.75 | PGR (0.32) | PGR | |
| SCHEMBL8948757 | 0.74 | MAPT (0.34) | — | |
| SCHEMBL8407415 | 0.72 | — | — | |
| SCHEMBL19042635 | 0.71 | NR3C1 (0.38) | PGRNR3C1AR | |
| SCHEMBL8410110 | 0.67 | PGR (0.36) | PGRNR3C1AR | |
| SCHEMBL5891966 | 0.67 | PGR (0.36) | PGRNR3C1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0565553-B1 | 6,7-MODIFIED 11$g(b)-ARYL-4-ESTRENES | SCHERING AG (DE) | 1999-07-21 | — | — | EP | disclosed |
| US-5843931-A | 6,7-modified 11β-aryl-4-oestrenes | SHERING AKTIENGESELLSCHAFT (DE) | 1998-12-01 | — | — | US | disclosed |