Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 2/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 14/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.35 |
| ▸ | STS | P08842 | 1/20 | 0.35 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.35 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8768139 | 1.00 | MAPT (0.39) | MAPTLMNAHSD17B1RECQLSMN1; SMN2 | |
| SCHEMBL8651638 | 1.00 | MAPT (0.39) | MAPTLMNAHSD17B1RECQLSMN1; SMN2 | |
| SCHEMBL8655553 | 0.88 | MAPT (0.35) | MAPTLMNAHSD17B1RECQLSMN1; SMN2 | |
| SCHEMBL8654560 | 0.88 | STS (0.38) | MAPTLMNAHSD17B1RECQLSMN1; SMN2 | |
| SCHEMBL8653384 | 0.83 | MAPT (0.38) | MAPTLMNAHSD17B1RECQLSMN1; SMN2 | |
| SCHEMBL8768961 | 0.82 | LMNA (0.38) | MAPTLMNASMN1; SMN2PGRNR3C1 | |
| SCHEMBL8653316 | 0.82 | LMNA (0.38) | MAPTLMNASMN1; SMN2PGRNR3C1 | |
| SCHEMBL9172523 | 0.82 | LMNA (0.38) | MAPTLMNASMN1; SMN2PGRNR3C1 | |
| SCHEMBL8656559 | 0.82 | NR3C1 (0.32) | PGRNR3C1AR | |
| SCHEMBL8653835 | 0.77 | MAPT (0.46) | MAPTLMNAHSD17B1RECQLSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5426102-A | Antigestagenic, antiandrogenic, antiglucocorticoid, antimineralcorticoid properties | SCHERING AKTIENGESELLSCHAFT (DE) | 1995-06-20 | — | — | US | disclosed |