Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 3/20 | 0.41 |
| ▸ | ELANE | P08246 | 17/20 | 0.39 |
| ▸ | CTRC | Q99895 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8654148 | 0.76 | ELANE (0.41) | ELANECTRC | |
| SCHEMBL8624804 | 0.75 | ELANE (0.46) | ELANECTRC | |
| SCHEMBL8628528 | 0.75 | ELANE (0.45) | ELANECTRC | |
| SCHEMBL7545819 | 0.71 | ELANE (0.58) | ELANECTRC | |
| SCHEMBL7440506 | 0.71 | ELANE (0.68) | ELANECTRC | |
| SCHEMBL7546824 | 0.68 | ELANE (0.54) | ELANECTRC | |
| SCHEMBL8994541 | 0.67 | ELANE (0.51) | ELANECTRC | |
| SCHEMBL8859916 | 0.61 | CASP1 (0.54) | CASP1 | |
| SCHEMBL7703522 | 0.61 | NPC1 (0.52) | CASP1ELANECTRC | |
| SCHEMBL23753620 | 0.59 | NPC1 (0.53) | CASP1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636142-B1 | LACTAM PEPTIDES HAVING HLE INHIBITING ACTIVITY | ZENECA LTD (GB) | 1998-06-17 | — | — | EP | disclosed |