Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.37 |
| ▸ | ESR1 | P03372 | 7/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.34 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.34 |
| ▸ | INSR | P06213 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CFTR | P13569 | 1/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8656916 | 0.93 | ESR1 (0.42) | PTPN1ESR1ESR2PPARGCCNB2 | |
| SCHEMBL8657893 | 0.88 | ESR1 (0.47) | PTPN1ESR1ESR2MAPK1ALDH1A1 | |
| SCHEMBL8653867 | 0.73 | PTPN1 (0.36) | PTPN1ESR1ESR2PPARGCCNB2 | |
| SCHEMBL8637350 | 0.65 | ALDH1A1 (0.53) | PTPN1PPARGMAPK1HSD17B3ALDH1A1 | |
| SCHEMBL8638111 | 0.65 | MEN1 (0.51) | PTPN1PPARGMAPK1ALOX5HSD17B3 | |
| SCHEMBL8653155 | 0.65 | ESR1 (0.39) | PTPN1ESR1ESR2PPARGCCNB2 | |
| SCHEMBL25144838 | 0.62 | ELANE (0.44) | MAPK1ALOX5ALDH1A1GAAABCB1 | |
| SCHEMBL25144976 | 0.60 | ELANE (0.44) | MAPK1HSD17B3ALDH1A1GAA | |
| SCHEMBL7371867 | 0.59 | TERT (0.64) | PTPN1ESR1ESR2MAPK1CDK5 | |
| SCHEMBL18770769 | 0.58 | TYR (0.49) | PTPN1ESR1ESR2CCNB2CCNE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0516257-B1 | Phenylbenzo[b]furans and -thiophenes, procedures for their preparation, and pharmaceutical compositions containing the same | SCHERING AG (DE) | 1998-08-05 | — | — | EP | claimed |