Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8659278 | 0.94 | SMN1; SMN2 (0.39) | SMN1; SMN2ALDH1A1KDM4EKMT2AKDM1A | |
| SCHEMBL8655552 | 0.94 | SMN1; SMN2 (0.34) | SMN1; SMN2KDM1A | |
| SCHEMBL8658988 | 0.93 | SMN1; SMN2 (0.38) | SMN1; SMN2ALDH1A1KDM4EKMT2A | |
| SCHEMBL8660886 | 0.92 | ITGB3 (0.32) | SMN1; SMN2KDM1ALMNA | |
| SCHEMBL8655456 | 0.90 | SMN1; SMN2 (0.34) | SMN1; SMN2ALDH1A1KMT2AKDM1AHPGD | |
| SCHEMBL8655360 | 0.89 | SMN1; SMN2 (0.34) | SMN1; SMN2 | |
| SCHEMBL8661310 | 0.89 | SMN1; SMN2 (0.39) | SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL8655580 | 0.89 | SMN1; SMN2 (0.39) | SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL8657958 | 0.89 | ITGB3 (0.32) | — | |
| SCHEMBL8661588 | 0.88 | SMN1; SMN2 (0.40) | SMN1; SMN2ALDH1A1KDM4EKDM1AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776937-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-07-07 | — | — | US | disclosed |