Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.33 |
| ▸ | TPSD1 | Q9BZJ3 | 3/20 | 0.33 |
| ▸ | TPSG1 | Q9NRR2 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | F10 | P00742 | 1/20 | 0.30 |
| ▸ | PLG | P00747 | 1/20 | 0.30 |
| ▸ | PLAU | P00749 | 1/20 | 0.30 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8661310 | 0.98 | SMN1; SMN2 (0.39) | SMN1; SMN2TPSAB1TPSD1TPSG1KDM4E | |
| SCHEMBL8661852 | 0.96 | SMN1; SMN2 (0.34) | SMN1; SMN2TPSAB1TPSD1TPSG1ALDH1A1 | |
| SCHEMBL8658243 | 0.94 | SMN1; SMN2 (0.34) | SMN1; SMN2TPSAB1TPSD1TPSG1ALDH1A1 | |
| SCHEMBL8655367 | 0.92 | TPSAB1 (0.33) | SMN1; SMN2TPSAB1TPSD1TPSG1F2 | |
| SCHEMBL8656251 | 0.91 | SMN1; SMN2 (0.34) | SMN1; SMN2TPSAB1TPSD1TPSG1ALDH1A1 | |
| SCHEMBL8659278 | 0.91 | SMN1; SMN2 (0.39) | SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL8654586 | 0.90 | TPSAB1 (0.33) | SMN1; SMN2TPSAB1TPSD1TPSG1F2 | |
| SCHEMBL8658988 | 0.90 | SMN1; SMN2 (0.38) | SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL8655681 | 0.90 | ITGB3 (0.34) | TPSAB1TPSD1TPSG1DRD2 | |
| SCHEMBL8654642 | 0.89 | SMN1; SMN2 (0.40) | SMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776937-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-07-07 | — | — | US | disclosed |