Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | STS | P08842 | 3/20 | 0.30 |
| ▸ | CA2 | P00918 | 2/20 | 0.30 |
| ▸ | CA9 | Q16790 | 2/20 | 0.30 |
| ▸ | FPR3 | P25089 | 1/20 | 0.30 |
| ▸ | FPR2 | P25090 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8655456 | 0.97 | SMN1; SMN2 (0.34) | SMN1; SMN2GLA | |
| SCHEMBL8658988 | 0.96 | SMN1; SMN2 (0.38) | SMN1; SMN2FPR3FPR2 | |
| SCHEMBL8655552 | 0.95 | SMN1; SMN2 (0.34) | SMN1; SMN2GLA | |
| SCHEMBL8659278 | 0.93 | SMN1; SMN2 (0.39) | SMN1; SMN2 | |
| SCHEMBL8658243 | 0.93 | SMN1; SMN2 (0.34) | SMN1; SMN2 | |
| SCHEMBL8656289 | 0.93 | OPRL1 (0.33) | — | |
| SCHEMBL8661852 | 0.91 | SMN1; SMN2 (0.34) | SMN1; SMN2 | |
| SCHEMBL8656251 | 0.90 | SMN1; SMN2 (0.34) | SMN1; SMN2 | |
| SCHEMBL8655698 | 0.90 | GAA (0.32) | SMN1; SMN2 | |
| SCHEMBL8659526 | 0.89 | ITGB3 (0.35) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776937-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-07-07 | — | — | US | disclosed |