Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MLYCD | O95822 | 2/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP7 | P09237 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | S100A4 | P26447 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24833896 | 0.82 | KMT2A (0.46) | KMT2AALDH1A1TP53LMNASMN1; SMN2 | |
| SCHEMBL3088547 | 0.82 | KMT2A (0.38) | KMT2AALDH1A1TP53LMNASMN1; SMN2 | |
| SCHEMBL3092037 | 0.80 | ALDH1A1 (0.40) | KMT2AALDH1A1TP53LMNASMN1; SMN2 | |
| SCHEMBL3096592 | 0.78 | MCL1 (0.40) | KMT2AALDH1A1TP53LMNASMN1; SMN2 | |
| SCHEMBL3100516 | 0.77 | CTSL (0.39) | KMT2AALDH1A1TP53LMNASMN1; SMN2 | |
| SCHEMBL13915059 | 0.77 | S100A4 (0.45) | KMT2AALDH1A1TP53LMNASMN1; SMN2 | |
| SCHEMBL3079169 | 0.76 | ALDH1A1 (0.40) | KMT2AALDH1A1TP53LMNASMN1; SMN2 | |
| SCHEMBL6762131 | 0.75 | ALDH1A1 (0.43) | KMT2AALDH1A1TP53LMNASMN1; SMN2 | |
| SCHEMBL3093425 | 0.75 | CTSL (0.41) | KMT2AALDH1A1TP53LMNASMN1; SMN2 | |
| SCHEMBL3469906 | 0.75 | HTT (0.37) | KMT2AALDH1A1TP53LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808152-A | Synthesis of N-(4-fluorophenyl)-2-hydroxy-N-(1-methylethyl)acetamide using sodium formate | BAYER CORPORATION (US) | 1998-09-15 | — | — | US | claimed |
| US-5808152-A | Synthesis of N-(4-fluorophenyl)-2-hydroxy-N-(1-methylethyl)acetamide using sodium formate | BAYER CORPORATION (US) | 1998-09-15 | — | — | US | disclosed |
| US-5808152-A | Synthesis of N-(4-fluorophenyl)-2-hydroxy-N-(1-methylethyl)acetamide using sodium formate | BAYER CORPORATION (US) | 1998-09-15 | — | — | US | disclosed |