Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8654791 | 0.97 | ALDH1A1 (0.42) | ALDH1A1KMT2AMEN1MAPTHTR7 | |
| SCHEMBL8657121 | 0.96 | CACNA1G (0.42) | ALDH1A1KMT2AMEN1MAPTHTR7 | |
| SCHEMBL8657670 | 0.94 | KMT2A (0.44) | ALDH1A1KMT2AMEN1MAPTHTR7 | |
| SCHEMBL8657783 | 0.94 | CACNA1G (0.42) | ALDH1A1KMT2AMEN1MAPTHTR7 | |
| SCHEMBL8658613 | 0.93 | ALDH1A1 (0.42) | ALDH1A1KMT2AMEN1MAPTTSHR | |
| SCHEMBL8655635 | 0.92 | ACHE (0.43) | — | |
| SCHEMBL8659466 | 0.92 | ACHE (0.43) | — | |
| SCHEMBL8657796 | 0.91 | KMT2A (0.43) | ALDH1A1KMT2AHTR7HTR1ATSHR | |
| SCHEMBL8654508 | 0.90 | ACHE (0.44) | — | |
| SCHEMBL8655866 | 0.90 | ALDH1A1 (0.41) | ALDH1A1KMT2AMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776937-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-07-07 | — | — | US | disclosed |