Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 5/20 | 0.43 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.42 |
| ▸ | CCR3 | P51677 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8654661 | 0.97 | CACNA1G (0.43) | HTR7CACNA1GCCR3HTR1AKMT2A | |
| SCHEMBL8654744 | 0.96 | HTR7 (0.43) | HTR7CCR3HTR1AKMT2A | |
| SCHEMBL8654558 | 0.95 | CACNA1G (0.43) | HTR7CACNA1GCCR3HTR1AKMT2A | |
| SCHEMBL8657942 | 0.94 | LTA4H (0.47) | — | |
| SCHEMBL8657796 | 0.93 | KMT2A (0.43) | HTR7CACNA1GCCR3HTR1AKMT2A | |
| SCHEMBL8657712 | 0.92 | SMN1; SMN2 (0.42) | HTR7CCR3HTR1A | |
| SCHEMBL8657296 | 0.92 | LTA4H (0.47) | — | |
| SCHEMBL8655861 | 0.91 | LTA4H (0.46) | — | |
| SCHEMBL8657783 | 0.91 | CACNA1G (0.42) | HTR7CACNA1GHTR1AKMT2A | |
| SCHEMBL8657864 | 0.89 | SMN1; SMN2 (0.43) | HTR7CCR3HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776937-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-07-07 | — | — | US | disclosed |