Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.69 |
| ▸ | RAB9A | P51151 | 5/20 | 0.69 |
| ▸ | NPC1 | O15118 | 4/20 | 0.69 |
| ▸ | LMNA | P02545 | 4/20 | 0.69 |
| ▸ | HTT | P42858 | 4/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.69 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.69 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.69 |
| ▸ | RELA | Q04206 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | TDP2 | O95551 | 2/20 | 0.57 |
| ▸ | NSD2 | O96028 | 2/20 | 0.57 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.57 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.57 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8654523 | 0.94 | MAPT (0.69) | MAPTSMN1; SMN2RAB9ANPC1LMNA | |
| SCHEMBL8654934 | 0.83 | MAPT (0.70) | MAPTSMN1; SMN2RAB9ANPC1LMNA | |
| SCHEMBL754259 | 0.82 | MAPT (1.00) | MAPTSMN1; SMN2RAB9ANPC1LMNA | |
| SCHEMBL29633257 | 0.82 | MAPT (1.00) | MAPTSMN1; SMN2RAB9ANPC1LMNA | |
| SCHEMBL28408126 | 0.80 | MAPT (0.96) | MAPTSMN1; SMN2RAB9ANPC1LMNA | |
| SCHEMBL8654199 | 0.79 | MAPT (0.55) | MAPTSMN1; SMN2RAB9ANPC1LMNA | |
| SCHEMBL8651079 | 0.77 | ALDH1A1 (0.56) | MAPTSMN1; SMN2RAB9ANPC1LMNA | |
| SCHEMBL8652412 | 0.77 | ALDH1A1 (0.66) | MAPTSMN1; SMN2RAB9ANPC1LMNA | |
| SCHEMBL8653946 | 0.75 | MAPT (0.58) | MAPTSMN1; SMN2RAB9ANPC1LMNA | |
| SCHEMBL8656023 | 0.75 | MAPT (0.68) | MAPTSMN1; SMN2RAB9ANPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0866692-A1 | USE OF BICYCLIC MONO- OR DIKETONE DERIVATIVES, RESULTING COMPOUNDS, AND USE THEREOF AS A DRUG FOR TREATING INFLAMMATION, MIGRAINE AND SHOCK | LABORATOIRE INNOTHERA Société Anonyme (FR) | 1998-09-30 | — | — | EP | claimed |
| WO-1997021432-A1 | USE OF BICYCLIC MONO- OR DIKETONE DERIVATIVES, RESULTING COMPOUNDS, AND USE THEREOF AS A DRUG FOR TREATING INFLAMMATION, MIGRAINE AND SHOCK | LABORATOIRE INNOTHERA, S.A. (FR) | 1997-06-19 | — | — | WO | claimed |