Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 6/20 | 0.34 |
| ▸ | DRD3 | P35462 | 6/20 | 0.34 |
| ▸ | DRD4 | P21917 | 4/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.33 |
| ▸ | FLT3 | P36888 | 2/20 | 0.33 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.33 |
| ▸ | MERTK | Q12866 | 2/20 | 0.33 |
| ▸ | GAS6 | Q14393 | 2/20 | 0.33 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.33 |
| ▸ | NPY2R | P49146 | 1/20 | 0.32 |
| ▸ | MTTP | P55157 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8650772 | 0.91 | CYP46A1 (0.39) | CNR1CNR2DRD2DRD3NPY2R | |
| SCHEMBL8651963 | 0.86 | CNR1 (0.40) | CNR1CNR2KMT2ADRD2DRD3 | |
| SCHEMBL8485533 | 0.85 | NPSR1 (0.42) | CNR1CNR2MEN1KMT2ADRD2 | |
| SCHEMBL8654362 | 0.84 | MEN1 (0.40) | CNR1CNR2MEN1KMT2ADRD2 | |
| SCHEMBL8648475 | 0.84 | CCR3 (0.39) | CNR1CNR2DRD2HTR1A | |
| SCHEMBL8717983 | 0.84 | CCR3 (0.43) | CNR1CNR2MEN1KMT2ADRD2 | |
| SCHEMBL8484454 | 0.83 | NPSR1 (0.42) | CNR1CNR2MEN1KMT2ADRD2 | |
| SCHEMBL8712537 | 0.82 | CCR3 (0.43) | CNR1CNR2MEN1KMT2ADRD2 | |
| SCHEMBL8713180 | 0.81 | CKS1B (0.41) | CNR1CNR2DRD2 | |
| SCHEMBL8665880 | 0.81 | UTS2R (0.39) | DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5712279-A | Inhibitors of microsomal triglyceride transfer protein and method | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-01-27 | — | — | US | disclosed |