Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 4/20 | 0.38 |
| ▸ | HTR4 | Q13639 | 4/20 | 0.38 |
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8651963 | 0.91 | CNR1 (0.40) | KMT2ADRD4DRD2DRD3CNR1 | |
| SCHEMBL8648475 | 0.86 | CCR3 (0.39) | TP53SMN1; SMN2DRD2CNR1CNR2 | |
| SCHEMBL8717983 | 0.86 | CCR3 (0.43) | MEN1KMT2AL3MBTL1DRD2CNR1 | |
| SCHEMBL8485533 | 0.85 | NPSR1 (0.42) | MEN1KMT2ADRD2DRD3HTR2A | |
| SCHEMBL8655291 | 0.84 | CNR1 (0.38) | MEN1KMT2ADRD4DRD2DRD3 | |
| SCHEMBL8712537 | 0.84 | CCR3 (0.43) | MEN1KMT2AL3MBTL1DRD2CNR1 | |
| SCHEMBL8484454 | 0.83 | NPSR1 (0.42) | MEN1KMT2ADRD2DRD3HTR2A | |
| SCHEMBL8665515 | 0.82 | CCR3 (0.41) | L3MBTL1DRD2CCR3LMNAMAPT | |
| SCHEMBL8713180 | 0.82 | CKS1B (0.41) | DRD2CNR1CNR2 | |
| SCHEMBL8654368 | 0.82 | DRD2 (0.38) | KMT2ADRD4HTR4DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5712279-A | Inhibitors of microsomal triglyceride transfer protein and method | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-01-27 | — | — | US | disclosed |