Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.33 |
| ▸ | TPSD1 | Q9BZJ3 | 3/20 | 0.33 |
| ▸ | TPSG1 | Q9NRR2 | 3/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.32 |
| ▸ | HRH1 | P35367 | 2/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
| ▸ | HTR4 | Q13639 | 6/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8658243 | 0.98 | SMN1; SMN2 (0.34) | SMN1; SMN2TPSAB1TPSD1TPSG1DRD2 | |
| SCHEMBL8656251 | 0.96 | SMN1; SMN2 (0.34) | SMN1; SMN2TPSAB1TPSD1TPSG1DRD2 | |
| SCHEMBL8655580 | 0.96 | SMN1; SMN2 (0.39) | SMN1; SMN2TPSAB1TPSD1TPSG1DRD2 | |
| SCHEMBL8661310 | 0.94 | SMN1; SMN2 (0.39) | SMN1; SMN2TPSAB1TPSD1TPSG1DRD2 | |
| SCHEMBL8655456 | 0.92 | SMN1; SMN2 (0.34) | SMN1; SMN2HRH1MEN1ALDH1A1KMT2A | |
| SCHEMBL8655367 | 0.91 | TPSAB1 (0.33) | SMN1; SMN2TPSAB1TPSD1TPSG1F2 | |
| SCHEMBL8655360 | 0.91 | SMN1; SMN2 (0.34) | SMN1; SMN2 | |
| SCHEMBL8656430 | 0.90 | ITGB3 (0.35) | SMN1; SMN2TPSAB1TPSD1TPSG1DRD2 | |
| SCHEMBL8655552 | 0.90 | SMN1; SMN2 (0.34) | SMN1; SMN2GAA | |
| SCHEMBL8654586 | 0.89 | TPSAB1 (0.33) | SMN1; SMN2TPSAB1TPSD1TPSG1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776937-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-07-07 | — | — | US | disclosed |