Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.31 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8658566 | 0.81 | TSHR (0.35) | TSHRSOS1SOS2 | |
| SCHEMBL9801465 | 0.78 | TSHR (0.36) | TSHRSOS1SOS2 | |
| SCHEMBL8655459 | 0.78 | TSHR (0.33) | TSHRSOS1SOS2 | |
| Piperazine SCHEMBL28095267 | 0.78 | TSHR (0.33) | TSHRSOS1SOS2 | |
| SCHEMBL28832205 | 0.78 | — | — | |
| Ammonia Solution, Strong SCHEMBL27506892 | 0.77 | TSHR (0.35) | TSHRSOS1SOS2 | |
| SCHEMBL25263941 | 0.75 | TSHR (0.34) | TSHRSOS1SOS2 | |
| SCHEMBL27638835 | 0.75 | TSHR (0.34) | TSHRSOS1SOS2 | |
| SCHEMBL28137826 | 0.73 | TSHR (0.31) | TSHR | |
| SCHEMBL12523367 | 0.72 | SOS1 (0.45) | TSHRSOS1SOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 215 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4253442-B1 | AMINE COMPOSITION USEFUL FOR MAKING STABLE POLYURETHANE FOAM SYSTEMS | EVONIK OPERATIONS GMBH (DE) | 2026-04-29 | — | — | EP | claimed |
| US-12540224-B2 | Process and composition for the production of flexible polyurethane foam | EVONIK OPERATIONS GMBH (DE) | 2026-02-03 | — | — | US | claimed |
| US-20260028445-A1 | AMINE COMPOSITION USEFUL FOR MAKING STABLE POLYURETHANE FOAM SYSTEMS | EVONIK OPERATIONS GMBH (DE) | 2026-01-29 | — | — | US | claimed |
| EP-4562070-A1 | METHOD FOR PREPARING FLEXIBLE SLABSTOCK POLYURETHANE FOAM | Evonik Operations GmbH (DE) | 2025-06-04 | — | — | EP | claimed |
| EP-4562069-A1 | TERTIARY AMINO-AMIDE COMPOSITION USEFUL IN MAKING POLYURETHANE POLYMERS | Evonik Operations GmbH (DE) | 2025-06-04 | — | — | EP | claimed |
| CN-119630722-A | Tertiary amino-amide compositions useful in the manufacture of polyurethane polymers | 赢创运营有限公司 | 2025-03-14 | — | — | CN | claimed |
| EP-3481878-B1 | AMINE COMPOSITION USEFUL FOR MAKING POLYURETHANE FOAM | EVONIK OPERATIONS GMBH (DE) | 2024-05-22 | — | — | EP | claimed |
| WO-2024022832-A1 | TERTIARY AMINO-AMIDE COMPOSITION USEFUL IN MAKING POLYURETHANE POLYMERS | EVONIK OPERATIONS GMBH (DE) | 2024-02-01 | — | — | WO | claimed |
| WO-2024022833-A1 | METHOD FOR PREPARING FLEXIBLE SLABSTOCK POLYURETHANE FOAM | EVONIK OPERATIONS GMBH (DE) | 2024-02-01 | — | — | WO | claimed |
| EP-4253442-A2 | AMINE COMPOSITION USEFUL FOR MAKING STABLE POLYURETHANE FOAM SYSTEMS | Evonik Operations GmbH (DE) | 2023-10-04 | — | — | EP | claimed |
| CN-106397730-A | Tertiary amine composition and method for making the composition | 气体产品与化学公司 | 2017-02-15 | — | — | CN | claimed |
| EP-2912080-B1 | AMINE CATALYST FOR IMPROVING THE STABILITY OF POLYURETHANE SYSTEMS HAVING HALOGEN CONTAINING BLOWING AGENTS | AIR PROD & CHEM (US) | 2016-08-17 | — | — | EP | claimed |
| US-20160222153-A1 | TERTIARY AMINE COMPOSITION AND METHOD FOR MAKING THE COMPOSITION | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2016-08-04 | — | — | US | claimed |
| US-9273175-B2 | Tertiary amine composition and method for making the composition | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2016-03-01 | — | — | US | claimed |
| US-20150266994-A1 | AMINE CATALYST FOR IMPROVING THE STABILITY OF POLYURETHANE SYSTEMS HAVING HALOGEN CONTAINING BLOWING AGENTS | EVONIK OPERATIONS GMBH (DE) | 2015-09-24 | — | — | US | claimed |
| EP-2912080-A1 | AMINE CATALYST FOR IMPROVING THE STABILITY OF POLYURETHANE SYSTEMS HAVING HALOGEN CONTAINING BLOWING AGENTS | Air Products and Chemicals, Inc. (US) | 2015-09-02 | — | — | EP | claimed |
| CN-103772634-A | Delayed action catalyst for improving the stability of polyurethane systems with halogen-containing blowing agents | AIR PROD & CHEM | 2014-05-07 | — | — | CN | claimed |
| WO-2014066596-A1 | AMINE CATALYST FOR IMPROVING THE STABILITY OF POLYURETHANE SYSTEMS HAVING HALOGEN CONTAINING BLOWING AGENTS | AIR PRODUCTS AND CHEMICALS, INC (US) | 2014-05-01 | — | — | WO | claimed |
| EP-2725047-A1 | Delay action catalyst for improving the stability of polyurethane systems having halogen containing blowing agents | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2014-04-30 | — | — | EP | claimed |
| US-20140113984-A1 | Delay Action Catalyst for Improving The Stability of Polyurethane Systems Having Halogen Containing Blowing Agents | EVONIK OPERATIONS GMBH (DE) | 2014-04-24 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12540224-B2 | Process and composition for the production of flexible polyurethane foam | INTS9, PUF60, INTS6 | TSHR 1697/4885SOS1 3876/4885SOS2 4170/4885 |
| US-20260028445-A1 | AMINE COMPOSITION USEFUL FOR MAKING STABLE POLYURETHANE FOAM SYSTEMS | RFC2, RFC3, PUF60 | TSHR 3699/4885SOS1 3751/4885SOS2 3968/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.