Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | FFAR2 | O15552 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7961516 | 0.89 | GPR88 (0.40) | GAASMN1; SMN2HSD11B1 | |
| SCHEMBL6474509 | 0.89 | UTS2R (0.38) | GAAHPGDSMN1; SMN2SLC6A2SLC6A4 | |
| SCHEMBL8657729 | 0.88 | GAA (0.37) | P2RX7GAAHPGDSMN1; SMN2FFAR2 | |
| SCHEMBL8655548 | 0.87 | GAA (0.38) | P2RX7GAAHPGDSMN1; SMN2FFAR2 | |
| SCHEMBL8651348 | 0.85 | GAA (0.38) | P2RX7GAAHPGDSMN1; SMN2FFAR2 | |
| SCHEMBL8653787 | 0.85 | GAA (0.38) | P2RX7GAAHPGDSMN1; SMN2FFAR2 | |
| SCHEMBL8652033 | 0.84 | GAA (0.37) | P2RX7GAAHPGDSMN1; SMN2FFAR2 | |
| SCHEMBL8886135 | 0.82 | P2RX7 (0.38) | P2RX7GAAHPGDSMN1; SMN2FFAR2 | |
| SCHEMBL8657265 | 0.82 | P2RX7 (0.36) | P2RX7GAAHPGDSMN1; SMN2FFAR2 | |
| SCHEMBL8650851 | 0.80 | ADRA1D (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5847211-A | Substituted 1H-3-Aryl-pyrrolidine-2,4-dione derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1998-12-08 | — | — | US | disclosed |
| US-5622917-A | PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-04-22 | — | — | US | disclosed |