⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5190067 | 0.71 | — | — | |
| SCHEMBL22069 | 0.71 | — | — | |
| SCHEMBL4558728 | 0.71 | LMNA (0.38) | — | |
| SCHEMBL8658286 | 0.70 | LMNA (0.34) | — | |
| SCHEMBL6278824 | 0.69 | LMNA (0.36) | — | |
| SCHEMBL6162987 | 0.69 | LMNA (0.36) | — | |
| Methyl Alcohol SCHEMBL7188450 | 0.67 | MMP2 (0.35) | — | |
| Formaldehyde SCHEMBL1396256 | 0.67 | LMNA (0.35) | — | |
| SCHEMBL14446948 | 0.64 | — | — | |
| Ethylene Glycol SCHEMBL6848838 | 0.62 | LMNA (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5733922-A | Imidazole derivative, pharmaceutically acceptable salt thereof, and anti-ulcer drug including such derivative or salt | ARAX CO., LTD. (JP) | 1998-03-31 | — | — | US | disclosed |
| EP-0728747-A1 | Imidazole derivative, pharmaceutically acceptable salt thereof, process of manufacture therefor, and anti-ulcer drug including such derivative or salt | ARAX CO., LTD. (JP) | 1996-08-28 | — | — | EP | disclosed |