Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13209004 | 0.76 | LMNA (0.48) | LMNANPSR1TSHRKDM4ECYP2C19 | |
| SCHEMBL542612 | 0.76 | LMNA (0.48) | LMNANPSR1TSHRKDM4ECYP2C19 | |
| SCHEMBL13209012 | 0.76 | LMNA (0.48) | LMNANPSR1TSHRKDM4ECYP2C19 | |
| SCHEMBL11495122 | 0.76 | LMNA (0.31) | LMNA | |
| SCHEMBL8655583 | 0.70 | — | — | |
| SCHEMBL14463632 | 0.68 | LMNA (0.39) | LMNANPSR1TSHRKDM4ECYP2C19 | |
| SCHEMBL6231321 | 0.64 | — | — | |
| SCHEMBL1404438 | 0.64 | SMN1; SMN2 (0.49) | LMNANPSR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL27816191 | 0.64 | LMNA (0.70) | LMNANPSR1TSHRKDM4ESMN1; SMN2 | |
| Hydantoin SCHEMBL9818415 | 0.63 | LMNA (0.35) | LMNANPSR1TSHRKDM4ECYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5733922-A | Imidazole derivative, pharmaceutically acceptable salt thereof, and anti-ulcer drug including such derivative or salt | ARAX CO., LTD. (JP) | 1998-03-31 | — | — | US | disclosed |
| EP-0728747-A1 | Imidazole derivative, pharmaceutically acceptable salt thereof, process of manufacture therefor, and anti-ulcer drug including such derivative or salt | ARAX CO., LTD. (JP) | 1996-08-28 | — | — | EP | disclosed |
| US-4724200-A | CRYSTAL STRUCTURE | EASTMAN KODAK COMPANY (US) | 1988-02-09 | — | — | US | disclosed |
| US-4680255-A | Emulsions and photographic elements containing silver halide grains having tetrahexahedral crystal faces | EASTMAN KODAK COMPANY (US) | 1987-07-14 | — | — | US | disclosed |
| US-4680254-A | Emulsions and photographic elements containing silver halide grains having hexoctamedral crystal faces | EASTMAN KODAK COMPANY (US) | 1987-07-14 | — | — | US | disclosed |
| US-4680256-A | Emulsions and photographic elements containing silver halide grains having trisoctahedra crystal faces | EASTMAN KODAK COMPANY (US) | 1987-07-14 | — | — | US | disclosed |
| US-4047953-A | PHOTOGRAPHIC FILMS | EASTMAN KODAK COMPANY (US) | 1977-09-13 | — | — | US | disclosed |