Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 2/20 | 0.48 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.46 |
| ▸ | HTR2A | P28223 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8625715 | 0.98 | GABBR2 (0.50) | GABBR2GABBR1CYP2C19TAAR1HTR2A | |
| SCHEMBL252241 | 0.98 | GABBR2 (0.50) | GABBR2GABBR1CYP2C19TAAR1HTR2A | |
| SCHEMBL8623471 | 0.98 | GABBR2 (0.50) | GABBR2GABBR1CYP2C19TAAR1HTR2A | |
| Hydrochloric Acid SCHEMBL2236710 | 0.96 | GABBR2 (0.48) | GABBR2GABBR1CYP2C19TAAR1HTR2A | |
| SCHEMBL9003499 | 0.85 | CYP2C19 (0.55) | GABBR2GABBR1CYP2C19TAAR1HTR2A | |
| SCHEMBL11364164 | 0.82 | HRH1 (0.52) | GABBR2GABBR1CYP2C19TAAR1HTR2A | |
| SCHEMBL6986752 | 0.80 | HTR2A (0.47) | GABBR2GABBR1CYP2C19TAAR1HTR2A | |
| SCHEMBL5879213 | 0.80 | HTR2A (0.47) | GABBR2GABBR1CYP2C19TAAR1HTR2A | |
| SCHEMBL5879215 | 0.80 | HTR2A (0.47) | GABBR2GABBR1CYP2C19TAAR1HTR2A | |
| SCHEMBL1610252 | 0.79 | CYP2C19 (0.50) | GABBR2GABBR1CYP2C19TAAR1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0843682-A1 | HIGH PURITY FORMULATIONS OF HIGHLY SUBSTITUTED LITHIUM AMIDE BASES | FMC CORPORATION (US) | 1998-05-27 | — | — | EP | disclosed |
| WO-1997006173-A1 | HIGH PURITY FORMULATIONS OF HIGHLY SUBSTITUTED LITHIUM AMIDE BASES | FMC CORPORATION (US) | 1997-02-20 | — | — | WO | disclosed |