SCHEMBL252241

SCHEMBL252241

C=CCC(CN)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABBR2 O75899 2/20 0.50
GABBR1 Q9UBS5 2/20 0.50
CYP2C19 P33261 1/20 0.48
TAAR1 Q96RJ0 4/20 0.48
HTR2A P28223 3/20 0.48
SMN1; SMN2 Q16637 2/20 0.44
CHRNB2 P17787 1/20 0.41
CHRNA4 P43681 1/20 0.41
HRH1 P35367 2/20 0.40
ALDH1A1 P00352 2/20 0.40
KDM4E B2RXH2 1/20 0.40
MAPT P10636 1/20 0.40
ALOX15 P16050 1/20 0.40
HSD17B10 Q99714 1/20 0.40
SLC6A2 P23975 1/20 0.38
SLC6A4 P31645 1/20 0.38
SLC6A3 Q01959 1/20 0.38
CYP1A2 P05177 1/20 0.36
CYP2D6 P10635 1/20 0.36
PKM P14618 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8625715 1.00 GABBR2 (0.50) GABBR2GABBR1CYP2C19TAAR1HTR2A
SCHEMBL8623471 1.00 GABBR2 (0.50) GABBR2GABBR1CYP2C19TAAR1HTR2A
Hydrochloric Acid SCHEMBL2236710 0.98 GABBR2 (0.48) GABBR2GABBR1CYP2C19TAAR1HTR2A
SCHEMBL8655741 0.98 GABBR2 (0.48) GABBR2GABBR1CYP2C19TAAR1HTR2A
SCHEMBL9003499 0.87 CYP2C19 (0.55) GABBR2GABBR1CYP2C19TAAR1HTR2A
SCHEMBL11364164 0.84 HRH1 (0.52) GABBR2GABBR1CYP2C19TAAR1HTR2A
SCHEMBL6986752 0.82 HTR2A (0.47) GABBR2GABBR1CYP2C19TAAR1HTR2A
SCHEMBL5879213 0.82 HTR2A (0.47) GABBR2GABBR1CYP2C19TAAR1HTR2A
SCHEMBL5879215 0.82 HTR2A (0.47) GABBR2GABBR1CYP2C19TAAR1HTR2A
SCHEMBL1610252 0.81 CYP2C19 (0.50) GABBR2GABBR1CYP2C19TAAR1HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 180 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116283672-B Synthesis method and application of beta-allyl phenethylamine derivative 四川师范大学 2024-09-17 CN claimed
CN-116283672-A Synthesis method and application of beta-allyl phenethylamine derivative 四川师范大学 2023-06-23 CN claimed
WO-2020162723-A1 POROUS LIQUID COMPOSITION COMPRISING METAL-ORGANIC UNIT, POROUS POLYMER COMPOSITION, AND PREPARATION METHOD THEREFOR 숙명여자대학교산학협력단 2020-08-13 WO claimed
US-7803146-B2 Sweat-absorbent sheet and process for making the same UNI-CHARM CORPORATION (JP) 2010-09-28 US claimed
EP-1967626-A1 SWEAT-ABSORBENT SHEET AND METHOD FOR PRODUCTION THEREOF UNICHARM CORPORATION (JP) 2008-09-10 EP claimed
EP-1960379-A1 N-(1-ALKYL-2-PHENYLETHYL)-CARBOXAMIDE DERIVATIVES AND USE THEREOF AS FUNGICIDES Bayer CropScience S.A. (FR) 2008-08-27 EP claimed
EP-1960350-A1 NEW N-(1-METHYL-2PHENYLETHYL)BENZAMIDE DERIVATIVES BAYER CROPSCIENCE SA (FR) 2008-08-27 EP claimed
US-20070149933-A1 Sweat-Absorbent Sheet and Process for Making the Same UNI-CHARM CORPORATION (JP) 2007-06-28 US claimed
WO-2007060164-A1 N-(1-ALKYL-2-PHENYLETHYL)-CARBOXAMIDE DERIVATIVES AND USE THEREOF AS FUNGICIDES BAYER CROPSCIENCE SA (FR) 2007-05-31 WO claimed
WO-2007060162-A1 NEW N-(1-METHYL-2PHENYLETHYL)BENZAMIDE DERIVATIVES BAYER CROPSCIENCE SA (FR) 2007-05-31 WO claimed
WO-1997002210-A2 CONTAMINANT FREE ORGANOMETALLIC AMIDE COMPOSITIONS AND PROCESSES FOR MAKING SAME FMC CORPORATION (US) 1997-01-23 WO claimed
CN-116283672-B Synthesis method and application of beta-allyl phenethylamine derivative 四川师范大学 2024-09-17 CN disclosed
EP-4422618-A1 LOX ENZYME INHIBITING METHODS AND COMPOSITIONS Anovia Biosciences, Inc. (US) 2024-09-04 EP disclosed
US-20240238759-A1 Preparation Method for Super Absorbent Polymer LG CHEM, LTD. (KR) 2024-07-18 US disclosed
US-12016864-B2 LOX enzyme inhibiting methods and compositions ANOVIA BIOSCIENCES, INC. (US) 2024-06-25 US disclosed
EP-1582573-A2 Pressure-sensitive adhesive composition, pressure-sensitive adhesive sheets and surface protecting film Nitto Denko Corporation (JP) 2005-10-05 EP disclosed
CN-1667071-A Adhesive composition, adhesive sheets and surface protective film NITTO DENKO CORP (JP) 2005-09-14 CN disclosed
US-20050197450-A1 Pressure-sensitive adhesive composition, pressure-sensitive adhesive sheets and surface protecting film NITTO DENKO CORPORATION (JP) 2005-09-08 US disclosed
EP-1124554-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING TETRAHYDROISOQUINOLINE COMPOUNDS KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2001-08-22 EP disclosed
WO-2000023078-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING TETRAHYDROISOQUINOLINE COMPOUNDS KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2000-04-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12016864-B2 LOX enzyme inhibiting methods and compositions LOX, LOXL1, LOXL2 GABBR2 3207/4885GABBR1 3393/4885CYP2C19 506/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.