Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A known ✓ | P28223 | 3/20 | 0.46 |
| ▸ | SLC6A2 known ✓ | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 known ✓ | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A3 known ✓ | Q01959 | 2/20 | 0.41 |
| ▸ | HRH1 known ✓ | P35367 | 2/20 | 0.39 |
| ▸ | GABBR2 | O75899 | 2/20 | 0.48 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8623471 | 0.98 | GABBR2 (0.50) | GABBR2GABBR1CYP2C19TAAR1HTR2A | |
| SCHEMBL252241 | 0.98 | GABBR2 (0.50) | GABBR2GABBR1CYP2C19TAAR1HTR2A | |
| SCHEMBL8625715 | 0.98 | GABBR2 (0.50) | GABBR2GABBR1CYP2C19TAAR1HTR2A | |
| SCHEMBL8655741 | 0.96 | GABBR2 (0.48) | GABBR2GABBR1CYP2C19TAAR1HTR2A | |
| SCHEMBL9003499 | 0.85 | CYP2C19 (0.55) | GABBR2GABBR1CYP2C19TAAR1HTR2A | |
| SCHEMBL11364164 | 0.82 | HRH1 (0.52) | GABBR2GABBR1CYP2C19TAAR1HTR2A | |
| Hydrochloric Acid SCHEMBL10676327 | 0.80 | TAAR1 (0.62) | GABBR2GABBR1TAAR1HTR2ASLC6A2 | |
| SCHEMBL6986752 | 0.80 | HTR2A (0.47) | GABBR2GABBR1CYP2C19TAAR1HTR2A | |
| SCHEMBL5879213 | 0.80 | HTR2A (0.47) | GABBR2GABBR1CYP2C19TAAR1HTR2A | |
| SCHEMBL5879215 | 0.80 | HTR2A (0.47) | GABBR2GABBR1CYP2C19TAAR1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-63083289-A | — | — | None | — | — | JP | disclosed |
| JP-10182464-A | — | — | None | — | — | JP | disclosed |
| CN-107526256-B | Toner compositions with anti-plasticizers | 施乐公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-112055581-B | Ultrasound-induced drug delivery system using drug carrier comprising nanobubbles and drug | 三育大学校产学协力团 | 2023-04-07 | — | — | CN | disclosed |
| CN-115677896-A | Latex composition with pH-responsive resin particles | 施乐公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-115678343-A | Ink composition having PH-responsive resin particles | 施乐公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-115386031-A | Seeded emulsion polymerization process for latex and aqueous inkjet ink compositions prepared therefrom | 施乐公司 | 2022-11-25 | — | — | CN | disclosed |
| CN-115304960-A | Aqueous inkjet ink composition | 施乐公司 | 2022-11-08 | — | — | CN | disclosed |
| CN-114265290-A | Textile custom printed with antimicrobial nanoparticles | 施乐公司 | 2022-04-01 | — | — | CN | disclosed |
| CN-113912837-A | Highly spherical polyamide microparticles and synthesis methods related thereto | 施乐公司 | 2022-01-11 | — | — | CN | disclosed |
| US-6569907-B1 | Comprises exothermic reactions to release insecticidal ingredients into atmosphere; for use in automobiles, airplanes, trains, and/or rooms equipped with metal goods or ornamental plants | EARTH CHEMICAL CO., LTD. (JP) | 2003-05-27 | — | — | US | disclosed |
| EP-1065252-A1 | HEAT TRANSPIRATION PREPARATION AND METHOD OF THE HEAT TRANSPIRATION OF CHEMICAL BY USING THE SAME | Earth Chemical Co., Ltd. (JP) | 2001-01-03 | — | — | EP | disclosed |
| JP-H10182464-A | EYE DROP SOLUTION | ASTA MEDICA AG | 1998-07-07 | — | — | JP | disclosed |
| EP-0439612-B1 | HEAT-SENSITIVE RECORDING PAPER | HONSHU PAPER CO LTD (JP) | 1994-09-14 | — | — | EP | disclosed |
| US-5338597-A | Substrate having ink-receiving layer containing basic magnesium carbonate and cationic and/or nonionic surfactant; images with consistent color tone | CANON KABUSHIKI KAISHA (JP) | 1994-08-16 | — | — | US | disclosed |
| EP-0249380-B1 | Shade enhancing agent | KAO CORP (JP) | 1993-11-03 | — | — | EP | disclosed |
| US-5126392-A | Color deepening with emulsion-polymerized resin and cationic protective colloid | KAO CORPORATION (JP) | 1992-06-30 | — | — | US | disclosed |
| EP-0439612-A1 | HEAT-SENSITIVE RECORDING PAPER | HONSHU PAPER CO., LTD. (JP) | 1991-08-07 | — | — | EP | disclosed |
| JP-S6383289-A | PRODUCTION OF 3-HYDROXYBENZYL ALCOHOL | MITSUI TOATSU CHEM INC | 1988-04-13 | — | — | JP | disclosed |
| EP-0249380-A2 | Shade enhancing agent | Kao Corporation (JP) | 1987-12-16 | — | — | EP | disclosed |