SCHEMBL8655829

SCHEMBL8655829

C=CC(=O)N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O

nearest known ligand 0.54

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.54
KDM4E B2RXH2 1/20 0.54
CYP2D6 P10635 1/20 0.54
CYP2C19 P33261 1/20 0.54
HK2 P52789 5/20 0.53
HK1 P19367 4/20 0.52
MAPK1 P28482 1/20 0.43
PYGB P11216 6/20 0.40
GAA P10253 1/20 0.40
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
ALDH1A1 P00352 1/20 0.38
THRB P10828 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31343127 1.00 LMNA (0.54) LMNAKDM4ECYP2D6CYP2C19HK2
SCHEMBL8655831 1.00 LMNA (0.54) LMNAKDM4ECYP2D6CYP2C19HK2
SCHEMBL31754235 1.00 LMNA (0.54) LMNAKDM4ECYP2D6CYP2C19HK2
SCHEMBL15686248 0.84 HK2 (0.40) LMNAKDM4ECYP2D6CYP2C19HK2
SCHEMBL31507892 0.83 LGALS3 (0.49) LMNAKDM4ECYP2D6CYP2C19HK2
SCHEMBL1302590 0.81 LMNA (0.57) LMNAKDM4ECYP2D6CYP2C19HK2
SCHEMBL1303257 0.81 LMNA (0.57) LMNAKDM4ECYP2D6CYP2C19HK2
SCHEMBL20852300 0.81 HK2 (0.56) LMNAKDM4ECYP2D6CYP2C19HK2
SCHEMBL24256660 0.81 CA2 (0.60) MAPK1PYGBCA2CA9ALDH1A1
SCHEMBL25867393 0.81 CA2 (0.60) MAPK1PYGBCA2CA9ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115531554-B Synthetic lethal nano-drug combination carrier and application thereof in preparation of GBM targeted drugs 河南大学 2023-08-11 CN claimed
CN-115531554-A Synthetic lethal nano-drug combined carrier and application thereof in preparation of GBM targeted drugs 河南大学 2022-12-30 CN claimed
JP-10298039-A None JP disclosed
US-20260002000-A1 HYBRID POLYMERS AND COMPOSITIONS INCLUDING THE SAME REGENTS OF THE UNIVERSITY OF MINNESOTA 2026-01-01 US disclosed
US-20250205359-A1 FERRISILICATE COMPOSITION AND METHOD FOR TREATING INSULIN DEFICIENCY IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) 2025-06-26 US disclosed
CN-119985995-A Compositions and methods for detecting traumatic brain injury 阿米达斯公司 2025-05-13 CN disclosed
US-12280125-B2 Method for delivering insulin IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) 2025-04-22 US disclosed
CN-112424606-B9 Compositions and methods for detecting traumatic brain injury 阿米达斯公司 2025-03-07 CN disclosed
CN-112424606-B Compositions and methods for detecting traumatic brain injury 阿米达斯公司 2025-01-14 CN disclosed
US-20240082422-A1 METHOD FOR DELIVERING INSULIN IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) 2024-03-14 US disclosed
CN-115531554-A Synthetic lethal nano-drug combined carrier and application thereof in preparation of GBM targeted drugs 河南大学 2022-12-30 CN disclosed
JP-H10298039-A USE OF 2,3-DIHYDROXYPROPYL 2-(1-OXOALKYL)AMINO-2-DEOXYGLUCOPYRANOSIDE IN DEPILATION THERAPEUTIC AGENT ELF ATOCHEM SA 1998-11-10 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260002000-A1 HYBRID POLYMERS AND COMPOSITIONS INCLUDING THE SAME H1-3, H1-2, H1-0 LMNA 1370/4885KDM4E 1469/4885CYP2D6 3322/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.