SCHEMBL865586

SCHEMBL865586

C=C(CCC(O)COc1ccccc1-c1ccccc1)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 2/20 0.51
ADRB1 P08588 1/20 0.51
ALDH1A1 P00352 6/20 0.46
MAPT P10636 1/20 0.46
ADRA1A P35348 1/20 0.46
TP53 P04637 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2D6 P10635 1/20 0.46
TSHR P16473 1/20 0.46
CYP2C19 P33261 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
SMN1; SMN2 Q16637 3/20 0.45
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
KDM4E B2RXH2 9/20 0.45
HTT P42858 2/20 0.44
RXRA P19793 1/20 0.43
RXRB P28702 1/20 0.43
RXRG P48443 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1535473 0.86 ALDH1A1 (0.54) ADRB2ADRB1ALDH1A1MAPTADRA1A
SCHEMBL866457 0.81 CYP1A2 (0.58) ADRB2ADRB1ALDH1A1MAPTADRA1A
SCHEMBL131675 0.80 TBXA2R (0.46) ADRB2ADRB1MAPTCYP1A2CYP2D6
SCHEMBL156467 0.80 KDM4E (0.58) ALDH1A1TP53TDP1L3MBTL1SMN1; SMN2
SCHEMBL6744564 0.80 KDM4E (0.48) ALDH1A1L3MBTL1SMN1; SMN2MEN1KMT2A
SCHEMBL628327 0.80 ADRB2 (0.61) ADRB2ADRB1ALDH1A1MAPTADRA1A
SCHEMBL450012 0.79 LMNA (0.58) ALDH1A1TP53L3MBTL1SMN1; SMN2MEN1
SCHEMBL15239093 0.78 PRMT5 (0.46) RXRARXRB
SCHEMBL19458668 0.78 KDM4E (0.60) ALDH1A1TP53L3MBTL1SMN1; SMN2MEN1
SCHEMBL10485548 0.77 ADRB2 (0.58) ADRB2ADRB1ALDH1A1MAPTADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9605143-B2 Resin composition for formation of optical waveguide, resin film for formation of optical waveguide which comprises the resin composition, and optical waveguide produced using the resin composition or the resin film HITACHI CHEMICALS COMPANY, LTD. (JP) 2017-03-28 US disclosed
US-8938135-B2 Method for manufacturing optical waveguide and optical waveguide manufactured by the method HITACHI CHEMICAL COMPANY, LTD. (JP) 2015-01-20 US disclosed
US-20150005406-A1 URETHANE (METH)ACRYLATE AND MOISTURE-PROOF INSULATING COATING MATERIAL SHOWA DENKO K.K. (JP) 2015-01-01 US disclosed
US-8787723-B2 Resin composition for forming optical waveguide, resin film for forming optical waveguide, and optical waveguide HITACHI CHEMICAL COMPANY, LTD. (JP) 2014-07-22 US disclosed
US-8632952-B2 Photosensitive resin composition, photosensitive resin cured matter, photosensitive resin film, photosensitive resin film cured matter and optical waveguide obtained by using the same HITACHI CHEMICAL COMPANY, LTD. (JP) 2014-01-21 US disclosed
EP-2045629-B1 RESIN COMPOSITION FOR OPTICAL WAVEGUIDE, RESIN FILM FOR OPTICAL WAVEGUIDE, AND OPTICAL WAVEGUIDE HITACHI CHEMICAL CO LTD (JP) 2013-09-04 EP disclosed
US-20130223803-A1 RESIN COMPOSITION FOR FORMATION OF OPTICAL WAVEGUIDE, RESIN FILM FOR FORMATION OF OPTICAL WAVEGUIDE WHICH COMPRISES THE RESIN COMPOSITION, AND OPTICAL WAVEGUIDE PRODUCED USING THE RESIN COMPOSITION OR THE RESIN FILM HITACHI CHEMICAL COMPANY, LTD. (JP) 2013-08-29 US disclosed
US-20120076468-A1 RESIN COMPOSITION FOR FORMING OPTICAL WAVEGUIDE, RESIN FILM FOR FORMING OPTICAL WAVEGUIDE, AND OPTICAL WAVEGUIDE HITACHI CHEMICAL COMPANY, LTD. (JP) 2012-03-29 US disclosed
US-8036511-B2 Resin composition for optical material, resin film for optical material, and optical waveguide HITACHI CHEMICAL COMPANY, LTD. (JP) 2011-10-11 US disclosed
US-20110075981-A1 RESIN COMPOSITION FOR OPTICAL MATERIAL, RESIN FILM FOR OPTICAL MATERIAL, AND OPTICAL WAVEGUIDE MAKINO TATSUYA 2011-03-31 US disclosed
US-7853113-B2 Resin composition for optical material, resin film for optical material, and optical waveguide HITACHI CHEMICAL COMPANY, LTD. (JP) 2010-12-14 US disclosed
US-20100221668-A1 RESIN COMPOSITION FOR OPTICAL MATERIAL, RESIN FILM FOR OPTICAL MATERIAL, AND OPTICAL WAVEGUIDE MAKINO TATSUYA 2010-09-02 US disclosed
US-7747129-B2 Resin composition for optical materials, resin film for optical material, and optical waveguide HITACHI CHEMICAL COMPANY, LTD. (JP) 2010-06-29 US disclosed
US-7660503-B2 Flexible optical waveguide and optical module HITACHI CHEMICAL COMPANY, LTD. (JP) 2010-02-09 US disclosed
US-20100027950-A1 PHOTOSENSITIVE RESIN COMPOSITION, PHOTOSENSITIVE RESIN CURED MATTER, PHOTOSENSITIVE RESIN FILM, PHOTOSENSITIVE RESIN FILM CURED MATTER AND OPTICAL WAVEGUIDE OBTAINED BY USING THE SAME HITACHI CHEMICAL COMPANY, LTD. (JP) 2010-02-04 US disclosed
US-20090196559-A1 Resin Composition for Optical Materials, Resin Film for Optical Material, and Optical Waveguide HITACHI CHEMICAL COMPANY, LTD. (JP) 2009-08-06 US disclosed
US-20090175585-A1 Flexible Optical Waveguide and Optical Module HITACHI CHEMICAL COMPANY, LTD. (JP) 2009-07-09 US disclosed
EP-2045629-A1 RESIN COMPOSITION FOR OPTICAL MATERIAL, RESIN FILM FOR OPTICAL MATERIAL, AND OPTICAL WAVEGUIDE Hitachi Chemical Company, Ltd. (JP) 2009-04-08 EP disclosed