SCHEMBL8655905

SCHEMBL8655905

COc1c[c]nc(OC)c1

nearest known ligand 0.38

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.35
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA7 P43166 1/20 0.32
CA9 Q16790 1/20 0.32
CA14 Q9ULX7 1/20 0.32
CCR1 P32246 1/20 0.31
CCR5 P51681 1/20 0.31
CCR8 P51685 1/20 0.31
PDE2A O00408 1/20 0.31
CYP1A1 P04798 2/20 0.30
CYP1B1 Q16678 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9481270 0.77
SCHEMBL3577843 0.77
SCHEMBL9481718 0.77 L3MBTL1 (0.44) ALDH1A1L3MBTL1CA12CA1CA2
SCHEMBL7758182 0.76
SCHEMBL4884574 0.72 ALDH1A1 (0.32) ALDH1A1
SCHEMBL9480201 0.71 RECQL (0.36)
SCHEMBL8563824 0.71 MAPT (0.33)
SCHEMBL7409975 0.70 LMNA (0.43) ALDH1A1L3MBTL1CA1CA2
SCHEMBL9479438 0.68 NQO1 (0.39) ALDH1A1
SCHEMBL3401912 0.67 ALDH1A1 (0.56) ALDH1A1L3MBTL1CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5770544-A TRIAZINES KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1998-06-23 US claimed
US-5616537-A Condensed heterocyclic derivatives and herbicides KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1997-04-01 US claimed
CN-1033201-C Herbicidal composition KUMIAI CHMICAL INDUSTRY CO LTD (JP) 1996-11-06 CN claimed
EP-0606489-A1 CONDENSED HETEROCYCLIC DERIVATIVE AND WEEDKILLER KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1994-07-20 EP claimed
CN-1072313-A Method with pyrimidine derivatives or its herbicidal salt KUMIAI CHEMICAL INDUSTRY CO (JP) 1993-05-26 CN claimed
EP-4396163-A1 HERBICIDAL MALONAMIDES CONTAINING MONOCYCLIC HETEROAROMATIC RINGS BASF SE (DE) 2024-07-10 EP disclosed
CN-117881662-A Herbicide malonamide containing monocyclic heteroaromatic ring 巴斯夫欧洲公司 2024-04-12 CN disclosed
WO-2023031199-A1 HERBICIDAL MALONAMIDES CONTAINING MONOCYCLIC HETEROAROMATIC RINGS BASF SE (DE) 2023-03-09 WO disclosed
CN-103931619-A Synergistic herbicidal composition containing certain pyridine or pyrimidine carboxylic acids and certain cereal and rice herbicides DOW AGROSCIENCES LLC 2014-07-23 CN disclosed
CN-101808520-B Synergistic herbicidal compositions containing certain pyridine or pyrimidine carboxylic acids and certain cereal and rice herbicides DOW AGROSCIENCES LLC 2014-06-18 CN disclosed
CN-101653136-B Herbicides with 4-iodo-2-[3-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)ureidosulfonyl]-benzoic acid esters HOECHST SCHERING AGREVO GMBH 2013-12-18 CN disclosed
CN-103415510-A Method for producing aminophenyl pyrimidinyl alcohol derivative, and synthesis intermediate thereof IHARA CHEMICAL IND CO 2013-11-27 CN disclosed
CN-1133038-A Substituted isoxazolines, process for producing them, agents containing them and their use as safeners HOECHST SCHERING AGREVO GMBH (DE) 1996-10-09 CN disclosed
EP-0606489-A1 CONDENSED HETEROCYCLIC DERIVATIVE AND WEEDKILLER KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1994-07-20 EP disclosed
CN-1023680-C Herbicidal pyridine sulfonylureas DU PONT (US) 1994-02-09 CN disclosed
EP-0247381-B1 5-FLUROROURACIL DERIVATIVES OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1993-08-04 EP disclosed
US-5047521-A Anticarcinogenic agents OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1991-09-10 US disclosed
CN-1050873-A The alkylsulfonyl guanylhydrazones that replaces BAYER AG (DE) 1991-04-24 CN disclosed
CN-87107320-A Herbicidal pyridine sulfonylureas 1988-12-07 CN disclosed
EP-0247381-A2 5-flurorouracil derivatives OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1987-12-02 EP disclosed