Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ESRRA | P11474 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KIT | P10721 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | PYGL | P06737 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8662507 | 0.92 | MAPT (0.48) | ALDH1A1GAASMN1; SMN2KMT2AMAPT | |
| SCHEMBL8657108 | 0.90 | PYGL (0.51) | ALDH1A1GAASMN1; SMN2KMT2AMAPT | |
| SCHEMBL8666493 | 0.88 | ALDH1A1 (0.53) | ALDH1A1GAASMN1; SMN2KMT2AMAPT | |
| SCHEMBL9132579 | 0.88 | ALDH1A1 (0.53) | ALDH1A1GAASMN1; SMN2KMT2AMAPT | |
| SCHEMBL8660780 | 0.88 | ALDH1A1 (0.59) | ALDH1A1GAASMN1; SMN2KMT2AMAPT | |
| SCHEMBL8663041 | 0.86 | ALDH1A1 (0.48) | ALDH1A1GAASMN1; SMN2KMT2AMAPT | |
| SCHEMBL8662761 | 0.86 | ESRRA (0.41) | ALDH1A1GAASMN1; SMN2KMT2AMAPT | |
| SCHEMBL8666779 | 0.86 | ALDH1A1 (0.49) | ALDH1A1GAASMN1; SMN2KMT2AMAPT | |
| SCHEMBL8660797 | 0.86 | ALDH1A1 (0.49) | ALDH1A1GAASMN1; SMN2KMT2AMAPT | |
| SCHEMBL8658825 | 0.85 | ALDH1A1 (0.54) | ALDH1A1GAASMN1; SMN2KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0124282-B1 | BICYCLOOXYARYL THIOUREAS AND PROCESS FOR PREPARATION | UNION CARBIDE CORPORATION (US) | 1987-09-30 | — | — | EP | claimed |
| EP-0124282-A1 | Bicyclooxyaryl thioureas and process for preparation | UNION CARBIDE CORPORATION (US) | 1984-11-07 | — | — | EP | claimed |
| US-5776981-A | Use of acyl urea compounds for controlling endoparasites and ectoparasites of warm-blooded animals | NOVARTIS CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| US-5776982-A | Use of acyl urea compounds for controlling endoparasites and ectoparasites of warm-blooded animals | NOVARTIS CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| US-5420163-A | Insecticides or miticides | CIBA-GEIGY (US) | 1995-05-30 | — | — | US | disclosed |
| US-5135953-A | Oral or injections; cattle, swine, poultry | CIBA-GEIGY (US) | 1992-08-04 | — | — | US | disclosed |
| EP-0211004-A1 | USE OF ACYL UREA COMPOUNDS FOR CONTROLLING ENDOPARASITES AND ECTOPARASITES OF WARM-BLOODED ANIMALS | RHONE-POULENC NEDERLAND B.V. (NL) | 1987-02-25 | — | — | EP | disclosed |
| WO-1986003941-A1 | USE OF ACYL UREA COMPOUNDS FOR CONTROLLING ENDOPARASITES AND ECTOPARASITES OF WARM-BLOODED ANIMALS | UNION CARBIDE CORPORATION (US) | 1986-07-17 | — | — | WO | disclosed |