Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 14/20 | 0.56 |
| ▸ | NPC1 | O15118 | 13/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11099353 | 0.91 | NPC1 (0.50) | RAB9ANPC1MEN1KMT2ARXFP1 | |
| SCHEMBL11189594 | 0.90 | RAB9A (0.47) | RAB9ANPC1MEN1KMT2ARXFP1 | |
| SCHEMBL11163699 | 0.86 | RAB9A (0.68) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11104934 | 0.84 | NPC1 (0.55) | RAB9ANPC1MEN1KMT2ARXFP1 | |
| SCHEMBL11522976 | 0.84 | RAB9A (0.45) | RAB9ANPC1MAPTKDM4E | |
| SCHEMBL11519534 | 0.83 | RAB9A (0.40) | RAB9ANPC1MEN1KMT2ARXFP1 | |
| SCHEMBL11015466 | 0.82 | RAB9A (0.55) | RAB9ANPC1MEN1KMT2ALMNA | |
| SCHEMBL11012517 | 0.82 | RAB9A (0.55) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11519411 | 0.81 | RAB9A (0.47) | RAB9ANPC1MAPTGAAKDM4E | |
| SCHEMBL8657584 | 0.81 | RAB9A (0.57) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0008880-B1 | 1-(2,6-DICHLOROBENZOYL)-3-(5-SUBSTITUTED-2-PYRIDINYL) UREAS, THEIR PREPARATION, FORMULATIONS AND USE AS INSECTICIDES | ELI LILLY AND COMPANY (US) | 1983-02-09 | — | — | EP | claimed |
| US-4219557-A | 1-(2,6-Dihalobenzoyl)-3-(5-substituted-2-pyridinyl)urea compounds and insecticidal use | ELI LILLY AND COMPANY (US) | 1980-08-26 | — | — | US | claimed |
| EP-0008880-A1 | 1-(2,6-Dichlorobenzoyl)-3-(5-substituted-2-pyridinyl) ureas, their preparation, formulations and use as insecticides | ELI LILLY AND COMPANY (US) | 1980-03-19 | — | — | EP | claimed |
| US-5776981-A | Use of acyl urea compounds for controlling endoparasites and ectoparasites of warm-blooded animals | NOVARTIS CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| US-5776982-A | Use of acyl urea compounds for controlling endoparasites and ectoparasites of warm-blooded animals | NOVARTIS CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| US-5420163-A | Insecticides or miticides | CIBA-GEIGY (US) | 1995-05-30 | — | — | US | disclosed |
| US-5135953-A | Oral or injections; cattle, swine, poultry | CIBA-GEIGY (US) | 1992-08-04 | — | — | US | disclosed |
| EP-0211004-A1 | USE OF ACYL UREA COMPOUNDS FOR CONTROLLING ENDOPARASITES AND ECTOPARASITES OF WARM-BLOODED ANIMALS | RHONE-POULENC NEDERLAND B.V. (NL) | 1987-02-25 | — | — | EP | disclosed |
| WO-1986003941-A1 | USE OF ACYL UREA COMPOUNDS FOR CONTROLLING ENDOPARASITES AND ECTOPARASITES OF WARM-BLOODED ANIMALS | UNION CARBIDE CORPORATION (US) | 1986-07-17 | — | — | WO | disclosed |
| EP-0008880-B1 | 1-(2,6-DICHLOROBENZOYL)-3-(5-SUBSTITUTED-2-PYRIDINYL) UREAS, THEIR PREPARATION, FORMULATIONS AND USE AS INSECTICIDES | ELI LILLY AND COMPANY (US) | 1983-02-09 | — | — | EP | disclosed |
| US-4219557-A | 1-(2,6-Dihalobenzoyl)-3-(5-substituted-2-pyridinyl)urea compounds and insecticidal use | ELI LILLY AND COMPANY (US) | 1980-08-26 | — | — | US | disclosed |
| EP-0008880-A1 | 1-(2,6-Dichlorobenzoyl)-3-(5-substituted-2-pyridinyl) ureas, their preparation, formulations and use as insecticides | ELI LILLY AND COMPANY (US) | 1980-03-19 | — | — | EP | disclosed |