SCHEMBL8656148

SCHEMBL8656148

O=C(O)CCCNC(=O)c1cc(O)ccc1O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.67
CDK1 P06493 1/20 0.52
KDM4E B2RXH2 1/20 0.51
ALDH1A1 P00352 1/20 0.51
HPGD P15428 1/20 0.51
ALOX5 P09917 3/20 0.51
PTGS2 P35354 3/20 0.51
SYK P43405 2/20 0.50
EGFR P00533 2/20 0.49
CA12 O43570 2/20 0.49
CA1 P00915 2/20 0.49
CA2 P00918 2/20 0.49
CA7 P43166 2/20 0.49
CA9 Q16790 2/20 0.49
CA14 Q9ULX7 2/20 0.49
CA3 P07451 1/20 0.49
CA4 P22748 1/20 0.49
CA6 P23280 1/20 0.49
CA5A P35218 1/20 0.49
CA13 Q8N1Q1 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11038520 0.94 NAAA (0.72) NAAACDK1KDM4EALDH1A1ALOX5
SCHEMBL5655974 0.94 NAAA (0.72) NAAACDK1KDM4EALDH1A1ALOX5
SCHEMBL2330956 0.85 CDK1 (0.74) NAAACDK1HPGDCA12CA1
SCHEMBL8658722 0.84 NAAA (0.66) NAAACDK1KDM4EALDH1A1ALOX5
SCHEMBL5656378 0.82 MAPK1 (0.58) NAAAKDM4EALDH1A1HPGDALOX5
SCHEMBL11026787 0.82 MAPK1 (0.58) NAAAKDM4EALDH1A1HPGDALOX5
SCHEMBL1707464 0.81 NPC1 (0.69) NAAAALDH1A1HPGDALOX5LMNA
SCHEMBL4622847 0.81 CDK1 (0.72) NAAACDK1HPGDCA12CA1
SCHEMBL15926284 0.81 NPC1 (0.74) NAAAKDM4EALDH1A1HPGDSYK
SCHEMBL13545501 0.81 MAPK1 (0.53) NAAACDK1KDM4EALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5854250-A N-benzoylamino acid derivatives, pharmaceutical compositions containing them and process of preparing same GYOGYSZERKUTATO INTEZET KFT (HU) 1998-12-29 US disclosed
US-5705529-A ANTIISCHEMIC AGENTS, ANTIINFLAMMATORY AGENTS, AGING RESISTANCE, ATHERIOSCLEROSIS, NERVOUS SYSTEM DISORDERS GYOGYSZERKUTATO INTEZET KFT (HK) 1998-01-06 US disclosed
EP-0576941-B1 N-benzoylamino acid derivatives, pharmaceutical compositions containing them and process for preparing same NISSHIN FLOUR MILLING CO (JP) 1997-09-03 EP disclosed
EP-0576941-A1 N-benzoylamino acid derivatives, pharmaceutical compositions containing them and process for preparing same NISSHIN FLOUR MILLING CO., LTD. (JP) 1994-01-05 EP disclosed