Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.53 |
| ▸ | EGFR | P00533 | 2/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.53 |
| ▸ | SYK | P43405 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CDK1 | P06493 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5655974 | 1.00 | NAAA (0.72) | NAAAMAPK1KDM4EALDH1A1POLB | |
| SCHEMBL8656148 | 0.94 | NAAA (0.67) | NAAAMAPK1KDM4EALDH1A1ALOX5 | |
| SCHEMBL11026787 | 0.88 | MAPK1 (0.58) | NAAAMAPK1KDM4EALDH1A1POLB | |
| SCHEMBL5656378 | 0.88 | MAPK1 (0.58) | NAAAMAPK1KDM4EALDH1A1POLB | |
| SCHEMBL14289170 | 0.86 | NAAA (0.57) | NAAAMAPK1KDM4EALDH1A1POLB | |
| SCHEMBL446310 | 0.86 | CDK1 (0.70) | NAAAMAPK1KDM4EALDH1A1POLB | |
| SCHEMBL2164508 | 0.86 | NAAA (0.57) | NAAAMAPK1KDM4EALDH1A1POLB | |
| SCHEMBL2158919 | 0.86 | ALDH1A1 (0.64) | NAAAMAPK1KDM4EALDH1A1POLB | |
| SCHEMBL30481047 | 0.86 | MAPK1 (0.63) | NAAAMAPK1KDM4EALDH1A1POLB | |
| SCHEMBL31661686 | 0.86 | NAAA (0.57) | NAAAMAPK1KDM4EALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0059108-B1 | DERIVATIVES OF DIHYDROXYBENZOIC ACID | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1985-08-14 | — | — | EP | disclosed |
| US-4409240-A | ANTICOAGULANTS, ANTIINFLAMMATORY AGENTS, HYPOTENSIVE AGENTS, BRONCHODILATOR, AND ANTIARTHRITIC AGENTS | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1983-10-11 | — | — | US | disclosed |
| EP-0059108-A1 | Derivatives of dihydroxybenzoic acid | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1982-09-01 | — | — | EP | disclosed |