SCHEMBL1707464

SCHEMBL1707464

O=C(O)CCCNC(=O)c1ccccc1O

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.69
ALDH1A1 P00352 1/20 0.69
MAPT P10636 1/20 0.69
HPGD P15428 1/20 0.69
TSHR P16473 1/20 0.69
HTT P42858 1/20 0.69
NPSR1 Q6W5P4 1/20 0.69
HSD17B10 Q99714 1/20 0.69
NLRP1 Q9C000 1/20 0.69
NAAA Q02083 1/20 0.65
ALOX5 P09917 1/20 0.58
MEN1 O00255 1/20 0.58
KMT2A Q03164 1/20 0.58
HIF1A Q16665 1/20 0.58
PPARG P37231 5/20 0.57
HDAC7 Q8WUI4 1/20 0.56
LMNA P02545 1/20 0.55
NAMPT P43490 1/20 0.55
NR1H4 Q96RI1 3/20 0.54
PPARA Q07869 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5655254 0.95 ALDH1A1 (0.68) NPC1ALDH1A1MAPTHPGDTSHR
SCHEMBL6383063 0.94 NAAA (0.70) NPC1ALDH1A1MAPTHPGDTSHR
SCHEMBL14088979 0.94 NAAA (0.70) NPC1ALDH1A1MAPTHPGDTSHR
SCHEMBL14088978 0.94 NAAA (0.70) NPC1ALDH1A1MAPTHPGDTSHR
SCHEMBL13593340 0.94 NAAA (0.70) NPC1ALDH1A1MAPTHPGDTSHR
SCHEMBL664024 0.94 NAAA (0.70) NPC1ALDH1A1MAPTHPGDTSHR
Salcaprozic Acid SCHEMBL4586235 0.94 NAAA (0.70) NPC1ALDH1A1MAPTHPGDTSHR
SCHEMBL2331916 0.94 NAAA (0.70) NPC1ALDH1A1MAPTHPGDTSHR
Salcaprozic Acid SCHEMBL29385752 0.94 NAAA (0.70) NPC1ALDH1A1MAPTHPGDTSHR
Salcaprozic Acid SCHEMBL845833 0.92 NAAA (0.68) NPC1ALDH1A1MAPTHPGDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1755578-B2 CHEWABLE, SUCKABLE AND SWALLOWABLE TABLET CONTAINING A CALCIUM-CONTAINING COMPOUND AS AN ACTIVE SUBSTANCE TAKEDA AS (NO) 2018-11-28 EP disclosed
US-9801907-B2 Film-coated and/or granulated calcium-containing compounds and use therof in pharmaceutical compositions TAKEDA AS (NO) 2017-10-31 US disclosed
EP-2409569-B1 Method for administering GLP-1 molecules EMISPHERE TECH INC (US) 2017-08-16 EP disclosed
EP-1478233-B1 METHOD FOR ADMINISTERING GLP-1 MOLECULES EMISPHERE TECH INC (US) 2016-11-09 EP disclosed
US-20150202296-A1 METHOD FOR ADMINISTERING GLP-1 MOLECULES NOVO NORDISK NORTH AMERICA OPERATIONS A/S (DK) 2015-07-23 US disclosed
US-20150202296-A1 METHOD FOR ADMINISTERING GLP-1 MOLECULES NOVO NORDISK NORTH AMERICA OPERATIONS A/S (DK) 2015-07-23 US disclosed
US-20150050353-A1 FILM-COATED AND/OR GRANULATED CALCIUM-CONTAINING COMPOUNDS AND USE THEROF IN PHARMACEUTICAL COMPOSITIONS TAKEDA AS (NO) 2015-02-19 US disclosed
US-8846088-B2 Melt granulation of a composition containing a calcium-containing compound TAKEDA NYCOMED AS (NO) 2014-09-30 US disclosed
US-8846101-B2 Film-coated and/or granulated calcium-containing compounds and use thereof in pharmaceutical compositions TAKEDA NYCOMED AS (NO) 2014-09-30 US disclosed
US-8808735-B2 Fast wet-massing method for the preparation of calcium-containing compositions TAKEDA NYCOMED AS (NO) 2014-08-19 US disclosed
EP-1755578-A2 CHEWABLE, SUCKABLE AND SWALLOWABLE TABLET CONTAINING A CALCIUM-CONTAINING COMPOUND AS AN ACTIVE SUBSTANCE Nycomed Pharma AS (NO) 2007-02-28 EP disclosed
WO-2006092727-A9 PROCESS FOR THE PRODUCTION OF CALCIUM COMPOSITIONS IN A CONTINUOUS FLUID BED NYCOMED PHARMA AS (NO) 2006-12-14 WO disclosed
WO-2006092727-A2 PROCESS FOR THE PRODUCTION OF CALCIUM COMPOSITIONS IN A CONTINUOUS FLUID BED NYCOMED PHARMA AS (NO) 2006-09-08 WO disclosed
WO-2006082499-A1 MELT GRANULATION OF A COMPOSITION CONTAINING A CALCIUM-CONTAINING COMPOUND NYCOMED PHARMA AS (NO) 2006-08-10 WO disclosed
WO-2006082501-A2 FAST WET-MASSING METHOD FOR THE PREPARATION OF CALCIUM-CONTAINING COMPOSITIONS NYCOMED PHARMA AS (NO) 2006-08-10 WO disclosed
CN-1816324-A Parathyroid hormone (pth) containing pharmaceutical compositions for oral use NYCOMED DANMARK APS (DK) 2006-08-09 CN disclosed
WO-2006046111-A1 USE OF XYLITOL AS AN ANTI-CHALK ACTING AGENT IN COMPOSITIONS FOR ORAL USE CONTAINING A CALCIUM-CONTAINING COMPOUND AS AN ACTIVE SUBSTANCE NYCOMED PHARMA AS (NO) 2006-05-04 WO disclosed
EP-1643978-A1 PARATHYROID HORMONE (PTH) CONTAINING PHARMACEUTICAL COMPOSITIONS FOR ORAL USE NYCOMED DANMARK A/S (DK) 2006-04-12 EP disclosed
WO-2005117829-A2 CHEWABLE, SUCKABLE AND SWALLOWABLE TABLET CONTAINING A CALCIUM-CONTAINING COMPOUND AS AN ACTIVE SUBSTANCE NYCOMED PHARMA AS (NO) 2005-12-15 WO disclosed
WO-2005002549-A1 PARATHYROID HORMONE (PTH) CONTAINING PHARMACEUTICAL COMPOSITIONS FOR ORAL USE NYCOMED DANMARK APS (DK) 2005-01-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150202296-A1 METHOD FOR ADMINISTERING GLP-1 MOLECULES GLP1R, GIPR, GPR119 NPC1 506/4885ALDH1A1 3386/4885MAPT 4362/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.