SCHEMBL8656152

SCHEMBL8656152

CCC(C)(C)c1ccc(OCCCC(=O)Nc2cc(Cl)c(C)c(Cl)c2O)c(C(C)(C)CC)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 5/20 0.44
NPSR1 Q6W5P4 5/20 0.44
SMN1; SMN2 Q16637 5/20 0.44
MEN1 O00255 5/20 0.44
KMT2A Q03164 5/20 0.44
ALDH1A1 P00352 1/20 0.44
MAPT P10636 7/20 0.44
HTT P42858 3/20 0.44
UBE2N P61088 2/20 0.44
GLA P06280 1/20 0.44
MITF O75030 1/20 0.42
RAB9A P51151 3/20 0.41
RAD52 P43351 2/20 0.41
STAT3 P40763 1/20 0.41
RCE1 Q9Y256 1/20 0.41
APAF1 O14727 1/20 0.41
HSP90AA1 P07900 1/20 0.41
NOD2 Q9HC29 1/20 0.41
KDM4E B2RXH2 2/20 0.40
RRM1 P23921 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8083289 0.90 SMN1; SMN2 (0.52) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL9550874 0.87 MAPK1 (0.44) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL11037770 0.84 SMN1; SMN2 (0.48) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL6568652 0.84 MEN1 (0.48) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL11475945 0.83 NPSR1 (0.39) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL11546383 0.81 MEN1 (0.47) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL8087137 0.81 HTT (0.43) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL15646925 0.80 POLB (0.39) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL7704204 0.80 NPSR1 (0.40) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL8075464 0.79 SMN1; SMN2 (0.51) MAPK1NPSR1SMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0599808-B1 Silver halide color photographic material FUJI PHOTO FILM CO LTD (JP) 1998-10-14 EP disclosed
US-4808515-A PYRAZOLOAZOLE COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1989-02-28 US disclosed
US-4745050-A Silver halide color photographic material and discoloration inhibitor therefor FUJI PHOTO FILM CO., LTD. (JP) 1988-05-17 US disclosed
EP-0217353-A2 Silver halide color photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1987-04-08 EP disclosed
US-4555479-A CONTAINING 5-PYRAZOLONE TYPE MAGENTA COUPLERS AND NITROGEN COMPOUND-PREVENTION STAINING FUJI PHOTO FILM CO., LTD. (JP) 1985-11-26 US disclosed
US-4463085-A SILVER HALIDE EMULSION, MAGENTA COUPLER CONTAINING PYRAZOL-5-ONE RING, AND PIPERIDINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1984-07-31 US disclosed
US-4264720-A CHROMENE COMPOUND COLOR STABILIZING AGENT FUJI PHOTO FILM CO., LTD. (JP) 1981-04-28 US disclosed
US-4263397-A SEALING A PACKAGE OF FILM HAVING A SILVER HALIDE EMULSION LAYER CONTAINING A SENSITIZING OR DESENSITIZING DYE; OXYGEN PERMEABILITY KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1981-04-21 US disclosed
US-4094684-A SILVER IODIDE, SILVER CHLORIDE EASTMAN KODAK COMPANY (US) 1978-06-13 US disclosed