SCHEMBL9550874

SCHEMBL9550874

CCC(C)(C)c1ccc(OCCCC(=O)Nc2c(O)cc(Cl)c(C)c2Cl)c(C(C)(C)CC)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 5/20 0.44
NPSR1 Q6W5P4 5/20 0.44
SMN1; SMN2 Q16637 5/20 0.44
MEN1 O00255 4/20 0.44
KMT2A Q03164 4/20 0.44
ALDH1A1 P00352 3/20 0.44
MAPT P10636 6/20 0.44
HTT P42858 3/20 0.44
UBE2N P61088 2/20 0.44
GLA P06280 1/20 0.44
MITF O75030 1/20 0.42
RAD52 P43351 2/20 0.41
RAB9A P51151 2/20 0.41
STAT3 P40763 1/20 0.41
RCE1 Q9Y256 1/20 0.41
APAF1 O14727 1/20 0.41
HSP90AA1 P07900 1/20 0.41
NOD2 Q9HC29 1/20 0.41
HPGD P15428 4/20 0.41
TSHR P16473 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8656152 0.87 MAPK1 (0.44) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL10732668 0.84 SMN1; SMN2 (0.48) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL6568652 0.82 MEN1 (0.48) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL10635099 0.80 NPSR1 (0.40) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL10763854 0.79 SMN1; SMN2 (0.51) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL11155394 0.78 MAPK1 (0.54) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL5675715 0.77 RAB9A (0.48) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL11624748 0.77 MEN1 (0.46) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL11546383 0.77 MEN1 (0.47) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL9869042 0.76 MEN1 (0.54) MAPK1NPSR1SMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5242789-A Photogrpahic films with 6-oxy substituted pyrazolo-triazole coupler FUJI PHOTO FILM CO., LTD. (JP) 1993-09-07 US disclosed
US-4882266-A Silver halide color photographic material containing a pyrazoloazole magenta coupler FUJI PHOTO FILM CO., LTD. (JP) 1989-11-21 US disclosed
US-H131-H HYDROXYPHENYL-CONTAINING PYRAZOLOAZOLE-TYPE MAGENTA COUPLERS; COLORFASTNESS FUJI PHOTO FILM CO., LTD. (JP) 1986-09-02 US disclosed
US-4552836-A CYAN DYE FORMING COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1985-11-12 US disclosed
US-4496650-A CYAN IMAGE FORMING POLYMER COUPLER LATEX FUJI PHOTO FILM CO., LTD. (JP) 1985-01-29 US disclosed
US-4430423-A CYAN DYE FORMING COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1984-02-07 US disclosed
US-4346165-A INCORPORATING METAL COMPLEX AND SPECIFIC DISCOLORATION INHIBITION AID FUJI PHOTO FILM CO., LTD. (JP) 1982-08-24 US disclosed
US-4297440-A CONTAINING A 3-ANILINO-5-PYRAZOLONE MAGENTA COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1981-10-27 US disclosed
US-4220711-A Silver halide color photographic light-sensitive element FUJI PHOTO FILM CO., LTD. (JP) 1980-09-02 US disclosed