Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8663031 | 0.87 | AKT1 (0.37) | POLBMEN1KMT2AMAPTAKT1 | |
| SCHEMBL8659450 | 0.86 | ALDH1A1 (0.38) | POLBMEN1KMT2AMAPTAKT1 | |
| SCHEMBL8660856 | 0.85 | MEN1 (0.45) | POLBMEN1KMT2AMAPTUSP2 | |
| SCHEMBL8669271 | 0.84 | MAPT (0.47) | POLBMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL8659527 | 0.83 | POLB (0.41) | POLBMEN1KMT2AMAPTUSP2 | |
| SCHEMBL8659947 | 0.83 | KMT2A (0.48) | POLBMEN1KMT2AMAPTUSP2 | |
| SCHEMBL9138737 | 0.82 | KMT2A (0.47) | POLBMEN1KMT2AMAPTUSP2 | |
| SCHEMBL8661113 | 0.81 | KMT2A (0.43) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL8660848 | 0.81 | MEN1 (0.42) | POLBMEN1KMT2AMAPTUSP2 | |
| SCHEMBL8662521 | 0.80 | ALDH1A1 (0.39) | POLBMEN1KMT2AMAPTAKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776981-A | Use of acyl urea compounds for controlling endoparasites and ectoparasites of warm-blooded animals | NOVARTIS CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| US-5776982-A | Use of acyl urea compounds for controlling endoparasites and ectoparasites of warm-blooded animals | NOVARTIS CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| US-5420163-A | Insecticides or miticides | CIBA-GEIGY (US) | 1995-05-30 | — | — | US | disclosed |
| US-5135953-A | Oral or injections; cattle, swine, poultry | CIBA-GEIGY (US) | 1992-08-04 | — | — | US | disclosed |