SCHEMBL8656270

SCHEMBL8656270

Cc1nnn(S)c1-c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.43
DRD4 P21917 1/20 0.43
DRD3 P35462 1/20 0.43
KMT2A Q03164 2/20 0.39
CYP1A2 P05177 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
BRD4 O60885 1/20 0.37
BRD2 P25440 1/20 0.37
BRD3 Q15059 1/20 0.37
TSHR P16473 3/20 0.37
ALDH1A1 P00352 2/20 0.37
NPC1 O15118 3/20 0.37
RAB9A P51151 3/20 0.37
SMN1; SMN2 Q16637 1/20 0.36
MAPK1 P28482 1/20 0.36
L3MBTL1 Q9Y468 3/20 0.35
AVPR1A P37288 1/20 0.35
POLB P06746 1/20 0.35
MAPT P10636 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9415763 0.79 MAPT (0.47) DRD2DRD4DRD3KMT2ACYP1A2
SCHEMBL8659186 0.77 NPC1 (0.44) KMT2AALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL11530601 0.76 CYP1A2 (0.50) DRD2DRD4DRD3CYP1A2CYP2C9
SCHEMBL11319766 0.75 ALDH1A1 (0.39) KMT2ACYP1A2CYP2C9CYP2C19BRD4
SCHEMBL27937742 0.73 DRD2 (0.43) DRD2DRD4DRD3CYP2C9CYP2C19
SCHEMBL28331497 0.72 CYP19A1 (0.58) DRD2DRD4DRD3TSHRALDH1A1
SCHEMBL27630917 0.71 DRD2 (0.41) DRD2DRD4DRD3CYP1A2CYP2C9
SCHEMBL2327352 0.68 ALDH1A1 (0.50) DRD4KMT2ATSHRALDH1A1SMN1; SMN2
SCHEMBL27572089 0.67 ALDH1A1 (0.49) DRD4KMT2ATSHRALDH1A1SMN1; SMN2
SCHEMBL27595506 0.67 ALDH1A1 (0.49) DRD4KMT2ATSHRALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0436027-B1 METHOD OF TREATING SILVER HALIDE PHOTOGRAPHIC MATERIAL FUJI PHOTO FILM CO LTD (JP) 1998-10-14 EP disclosed
US-5780198-A MULTILAYER; CONTAINS A HYDRAZINE NUCLEATING AGENT AND A REDOX COMPOUND CAPABLE OF RELEASING A DEVELOPMENT INHIBITOR WHEN THE REDOX COMPOUND IS OXIDIZED; ULTRAHIGH CONTRAST IMAGE WITH BROAD DOT GRADATION FUJI PHOTO FILM CO., LTD. (JP) 1998-07-14 US disclosed
EP-0442323-B1 Silver halide color reversal photographic material capable of providing interimage effect FUJI PHOTO FILM CO LTD (JP) 1997-10-15 EP disclosed
EP-0395069-B1 Silver halide photographic materials FUJI PHOTO FILM CO LTD (JP) 1996-07-10 EP disclosed
EP-0420005-B1 High contrast silver halide photographic material FUJI PHOTO FILM CO LTD (JP) 1996-07-10 EP disclosed
EP-0335319-B1 Silver halide photographic material FUJI PHOTO FILM CO LTD (JP) 1996-06-05 EP disclosed
EP-0398285-B1 Silver halide photographic materials FUJI PHOTO FILM CO LTD (JP) 1995-09-13 EP disclosed
EP-0393720-B1 Silver halide photographic materials FUJI PHOTO FILM CO LTD (JP) 1995-08-23 EP disclosed
US-5395732-A Silver halide photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1995-03-07 US disclosed
US-5262287-A Improved color reproducibility FUJI PHOTO FILM CO., LTD. (JP) 1993-11-16 US disclosed
US-5085971-A Redox system capable of releasing development inhibitor by oxidation and a hydrazine compound FUJI PHOTO FILM CO., LTD. (JP) 1992-02-04 US disclosed
EP-0442323-A2 Silver halide color reversal photographic material capable of providing interimage effect FUJI PHOTO FILM CO., LTD. (JP) 1991-08-21 EP disclosed
EP-0436027-A1 METHOD OF TREATING SILVER HALIDE PHOTOGRAPHIC MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1991-07-10 EP disclosed
US-5006444-A Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1991-04-09 US disclosed
EP-0420005-A1 high contrast silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1991-04-03 EP disclosed
EP-0398285-A2 Silver halide photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1990-11-22 EP disclosed
EP-0395069-A2 Silver halide photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1990-10-31 EP disclosed
EP-0393720-A2 Silver halide photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1990-10-24 EP disclosed
EP-0335319-A2 Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1989-10-04 EP disclosed
US-4737442-A INCLUDING A SENSITIZER AND A BLOCKED DEVELOPMENT RESTRAINER; FREE OF BLACK SPOTS FUJI PHOTO FILM CO., LTD. (JP) 1988-04-12 US disclosed