SCHEMBL8656286

SCHEMBL8656286

CCCCC(=CC=Cc1ccccc1)c1ccccc1CC

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.41
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
TDP1 Q9NUW8 2/20 0.39
LMNA P02545 4/20 0.38
ALDH1A1 P00352 4/20 0.38
GAA P10253 2/20 0.38
MAPT P10636 1/20 0.38
EGFR P00533 1/20 0.38
HDAC3 O15379 1/20 0.38
POLB P06746 2/20 0.38
RECQL P46063 1/20 0.37
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36
MAOB P27338 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2380962 0.81 KDM4E (0.48) KDM4EMEN1KMT2ATDP1LMNA
SCHEMBL23934240 0.74 GRIK1 (0.55) KDM4EMEN1KMT2ATDP1LMNA
SCHEMBL375312 0.74 GRIK1 (0.55) KDM4EMEN1KMT2ATDP1LMNA
SCHEMBL10902329 0.73 TDP1 (0.43) TDP1LMNAALDH1A1CES2CES1
SCHEMBL7214832 0.70 MCL1 (0.47) KDM4EMEN1KMT2ATDP1LMNA
SCHEMBL393958 0.70 GRIK1 (0.54) KDM4EMEN1KMT2ATDP1LMNA
Maleic Acid SCHEMBL8995943 0.69 GRIK1 (0.50) KDM4EMEN1KMT2ATDP1LMNA
(Z)-1,2-Diphenylethene SCHEMBL991412 0.69 PPARA (0.58) MEN1KMT2ATDP1LMNAALDH1A1
SCHEMBL9312348 0.69 F2R (0.44) TDP1ALDH1A1CES2CES1
(Z)-1,2-Diphenylethene SCHEMBL991411 0.69 PPARA (0.58) MEN1KMT2ATDP1LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4366515-A1 HOSE PIPE REHAU Industries SE & Co. KG (DE) 2024-05-15 EP claimed
WO-2023280521-A1 HOSE PIPE REHAU Industries SE & Co. KG (DE) 2023-01-12 WO claimed
EP-0771052-B1 Telephone line connector RAYCHEM CORP (US) 1998-10-14 EP claimed
US-5470634-A Cover for air-bag installation AUTOLIV DEVELOPMENT AB (SE) 1995-11-28 US claimed
EP-4366515-A1 HOSE PIPE REHAU Industries SE & Co. KG (DE) 2024-05-15 EP disclosed
WO-2023280521-A1 HOSE PIPE REHAU Industries SE & Co. KG (DE) 2023-01-12 WO disclosed
WO-2019076815-A1 TONOMETER CONE ARTEMA SRL (IT) 2019-04-25 WO disclosed
US-5470634-A Cover for air-bag installation AUTOLIV DEVELOPMENT AB (SE) 1995-11-28 US disclosed