SCHEMBL2380962

SCHEMBL2380962

CCCCC(=CC=Cc1ccccc1)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.48
PTGS2 P35354 1/20 0.45
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
POLB P06746 1/20 0.44
CES2 O00748 2/20 0.44
CES1 P23141 2/20 0.44
LMNA P02545 4/20 0.43
ALDH1A1 P00352 3/20 0.43
GAA P10253 1/20 0.42
MAPT P10636 1/20 0.42
MAOB P27338 1/20 0.41
TDP1 Q9NUW8 2/20 0.40
ESR1 P03372 1/20 0.40
EGFR P00533 1/20 0.39
HDAC3 O15379 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22192129 0.83 LMNA (0.48) KDM4EMEN1KMT2APOLBLMNA
SCHEMBL5101844 0.83 LMNA (0.48) KDM4EMEN1KMT2APOLBLMNA
SCHEMBL8656286 0.81 KDM4E (0.41) KDM4EMEN1KMT2APOLBCES2
SCHEMBL28643288 0.81 PTGS2 (0.45) PTGS2CES2CES1LMNAALDH1A1
SCHEMBL560984 0.80 LMNA (0.51) PTGS2MEN1KMT2ACES2CES1
SCHEMBL4264646 0.79 TUBB4A (0.40) KDM4ECES2CES1
SCHEMBL272292 0.78 CES2 (0.51) PTGS2CES2CES1LMNAALDH1A1
SCHEMBL28273252 0.78 PTGS2 (0.49) PTGS2CES2CES1LMNAALDH1A1
SCHEMBL29131554 0.78 PTGS2 (0.49) PTGS2CES2CES1LMNAALDH1A1
SCHEMBL28023700 0.77 LMNA (0.43) KDM4EMEN1KMT2APOLBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011160257-A1 METHOD AND APPARATUS FOR BONDING COMPOSITE SOLAR CELL STRUCTURE APPLIED MATERIALS, INC. (US) 2011-12-29 WO claimed
US-20020197471-A1 Compositions and methods of making temperature resistant protective tape SCAPA NORTH AMERICA 2002-12-26 US claimed
WO-2001078891-A9 APPARATUS AND METHOD FOR CONTINUOUS SURFACE MODIFICATION OF SUBSTRATES REIMER KARL (US) 2002-01-10 WO claimed
WO-2000001528-A1 METHODS FOR PLASMA MODIFICATION OF SUBSTRATES METROLINE INDUSTRIES, INC. (US) 2000-01-13 WO claimed
US-9200450-B2 Ridge cap with asphaltic foam materials DEVPAT, LLC (US) 2015-12-01 US disclosed
WO-2014126676-A1 EXTERIOR FACING STRETCH AND FLAME RESISTANT SEAM TAPE MASSIF MOUNTAIN GEAR CO., LLC (US) 2014-08-21 WO disclosed
US-20140223648-A1 Exterior Facing Stretch and Flame Resistant Seam Tape Massif Mountain Gear Company (US) 2014-08-14 US disclosed
US-20140033626-A1 RIDGE CAP WITH ASPHALTIC FOAM MATERIALS DEVPAT, LLC (US) 2014-02-06 US disclosed
US-8549802-B2 Ridge cap with asphaltic foam materials DEVPAT, LLC (US) 2013-10-08 US disclosed
US-20130036677-A1 RIDGE CAP WITH ASPHALTIC FOAM MATERIALS DEVPAT, LLC (US) 2013-02-14 US disclosed
WO-2011160257-A1 METHOD AND APPARATUS FOR BONDING COMPOSITE SOLAR CELL STRUCTURE APPLIED MATERIALS, INC. (US) 2011-12-29 WO disclosed
US-8017663-B2 Mold production of rigid roofing materials; liquefying asphalt, combining with polyisocyanate and heating; combining with mixture of polyols, blowing agent and surfactant then curing DEVPAT, LLC (US) 2011-09-13 US disclosed
WO-2000001528-A1 METHODS FOR PLASMA MODIFICATION OF SUBSTRATES METROLINE INDUSTRIES, INC. (US) 2000-01-13 WO disclosed
US-5965626-A Method of making rigid asphaltic foam FONTANA PAPER MILLS, INC. (US) 1999-10-12 US disclosed
EP-0787069-A4 ASPHALTIC FOAM THAGARD GEORGE F III (US) 1998-11-11 EP disclosed
US-5816014-A Method of making a ridge cap roofing tile FONTANA PAPER MILLS, INC. (US) 1998-10-06 US disclosed
US-5813176-A Asphaltic foam FONTANA PAPER MILLS, INC. (US) 1998-09-29 US disclosed
EP-0787069-A1 ASPHALTIC FOAM Thagard, George F. III (US) 1997-08-06 EP disclosed
WO-1996012619-A9 ASPHALTIC FOAM 1996-07-18 WO disclosed
WO-1996012619-A1 ASPHALTIC FOAM THAGARD GEORGE F III (US) 1996-05-02 WO disclosed