Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 4/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MME | P08473 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8651874 | 0.84 | MME (0.46) | KEAP1NFE2L2LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL6481469 | 0.83 | SMN1; SMN2 (0.52) | SMN1; SMN2ALDH1A1MEN1KMT2ATP53 | |
| SCHEMBL8657309 | 0.80 | ALDH1A1 (0.46) | LMNASMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL8653691 | 0.80 | MAPK1 (0.53) | LMNAALDH1A1MMEMEN1KMT2A | |
| SCHEMBL3383072 | 0.78 | LMNA (0.46) | KEAP1NFE2L2LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL25717182 | 0.78 | PRCP (0.49) | KEAP1NFE2L2LMNAMME | |
| SCHEMBL11836955 | 0.73 | FFAR1 (0.46) | LMNASMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL11773513 | 0.72 | CXCR1 (0.44) | KEAP1NFE2L2LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL8651984 | 0.72 | LMNA (0.40) | KEAP1NFE2L2LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL821456 | 0.72 | CA2 (0.63) | LMNASMN1; SMN2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5847211-A | Substituted 1H-3-Aryl-pyrrolidine-2,4-dione derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1998-12-08 | — | — | US | disclosed |
| US-5622917-A | PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-04-22 | — | — | US | disclosed |